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Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system.
Tiwari V, Prajapati B, Asare Y, Damkou A, Ji H, Liu L, Naser N, Gouna G, Leszczyńska KB, Mieczkowski J, Dichgans M, Wang Q, Kawaguchi R, Shi Z, Swarup V, Geschwind DH, Prinz M, Gokce O, Simons M. Tiwari V, et al. Among authors: mieczkowski j. Immunity. 2024 Sep 10;57(9):2173-2190.e8. doi: 10.1016/j.immuni.2024.07.001. Epub 2024 Jul 24. Immunity. 2024. PMID: 39053462 Free article.
H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells.
Leszczynska KB, Freitas-Huhtamäki A, Jayaprakash C, Dzwigonska M, Vitorino FNL, Horth C, Wojnicki K, Gielniewski B, Szadkowska P, Kaza B, Nazarian J, Ciolkowski MK, Trubicka J, Grajkowska W, Garcia BA, Majewski J, Kaminska B, Mieczkowski J. Leszczynska KB, et al. Among authors: mieczkowski j. Cell Rep. 2024 Feb 27;43(2):113707. doi: 10.1016/j.celrep.2024.113707. Epub 2024 Feb 1. Cell Rep. 2024. PMID: 38306270 Free PMC article.
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas.
Stępniak K, Machnicka MA, Mieczkowski J, Macioszek A, Wojtaś B, Gielniewski B, Poleszak K, Perycz M, Król SK, Guzik R, Dąbrowski MJ, Dramiński M, Jardanowska M, Grabowicz I, Dziedzic A, Kranas H, Sienkiewicz K, Diamanti K, Kotulska K, Grajkowska W, Roszkowski M, Czernicki T, Marchel A, Komorowski J, Kaminska B, Wilczyński B. Stępniak K, et al. Among authors: mieczkowski j. Nat Commun. 2021 Jun 15;12(1):3621. doi: 10.1038/s41467-021-23922-2. Nat Commun. 2021. PMID: 34131149 Free PMC article.
In Search for Reliable Markers of Glioma-Induced Polarization of Microglia.
Walentynowicz KA, Ochocka N, Pasierbinska M, Wojnicki K, Stepniak K, Mieczkowski J, Ciechomska IA, Kaminska B. Walentynowicz KA, et al. Among authors: mieczkowski j. Front Immunol. 2018 Jun 15;9:1329. doi: 10.3389/fimmu.2018.01329. eCollection 2018. Front Immunol. 2018. PMID: 29963047 Free PMC article.
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia.
Przanowski P, Dabrowski M, Ellert-Miklaszewska A, Kloss M, Mieczkowski J, Kaza B, Ronowicz A, Hu F, Piotrowski A, Kettenmann H, Komorowski J, Kaminska B. Przanowski P, et al. Among authors: mieczkowski j. J Mol Med (Berl). 2014 Mar;92(3):239-54. doi: 10.1007/s00109-013-1090-5. Epub 2013 Oct 6. J Mol Med (Berl). 2014. PMID: 24097101 Free PMC article.
90 results