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Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system.
Tiwari V, Prajapati B, Asare Y, Damkou A, Ji H, Liu L, Naser N, Gouna G, Leszczyńska KB, Mieczkowski J, Dichgans M, Wang Q, Kawaguchi R, Shi Z, Swarup V, Geschwind DH, Prinz M, Gokce O, Simons M. Tiwari V, et al. Among authors: shi z. Immunity. 2024 Sep 10;57(9):2173-2190.e8. doi: 10.1016/j.immuni.2024.07.001. Epub 2024 Jul 24. Immunity. 2024. PMID: 39053462 Free article.
A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. Tran KM, et al. Among authors: shi z, shi kx. Mol Neurodegener. 2023 Feb 17;18(1):12. doi: 10.1186/s13024-023-00598-4. Mol Neurodegener. 2023. PMID: 36803190 Free PMC article.
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease.
Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. Garcia-Agudo LF, et al. Among authors: shi z, shi kx. Alzheimers Dement. 2024 Apr;20(4):2922-2942. doi: 10.1002/alz.13767. Epub 2024 Mar 9. Alzheimers Dement. 2024. PMID: 38460121 Free PMC article.
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's disease.
Miyoshi E, Morabito S, Henningfield CM, Das S, Rahimzadeh N, Shabestari SK, Michael N, Emerson N, Reese F, Shi Z, Cao Z, Srinivasan SS, Scarfone VM, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M; Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC–DS); Head E, Green KN, Swarup V. Miyoshi E, et al. Among authors: shi z. Nat Genet. 2024 Dec;56(12):2704-2717. doi: 10.1038/s41588-024-01961-x. Epub 2024 Nov 22. Nat Genet. 2024. PMID: 39578645 Free PMC article.
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease.
Miyoshi E, Morabito S, Henningfield CM, Rahimzadeh N, Kiani Shabestari S, Das S, Michael N, Reese F, Shi Z, Cao Z, Scarfone V, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M, Head E, Green KN, Swarup V. Miyoshi E, et al. Among authors: shi z. bioRxiv [Preprint]. 2023 Jul 26:2023.07.24.550282. doi: 10.1101/2023.07.24.550282. bioRxiv. 2023. Update in: Nat Genet. 2024 Dec;56(12):2704-2717. doi: 10.1038/s41588-024-01961-x PMID: 37546983 Free PMC article. Updated. Preprint.
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