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281 results

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Page 1
Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose study.
van den Berg LH, Rothstein JD, Shaw PJ, Babu S, Benatar M, Bucelli RC, Genge A, Glass JD, Hardiman O, Libri V, Mobach T, Oskarsson B, Pattee GL, Ravits J, Shaw CE, Weber M, Zinman L, Jafar-Nejad P, Rigo F, Lin L, Ferguson TA, Gotter AL, Graham D, Monine M, Inra J, Sinks S, Eraly S, Garafalo S, Fradette S. van den Berg LH, et al. Among authors: benatar m. Lancet Neurol. 2024 Sep;23(9):901-912. doi: 10.1016/S1474-4422(24)00216-3. Epub 2024 Jul 23. Lancet Neurol. 2024. PMID: 39059407 Clinical Trial.
Selecting promising ALS therapies in clinical trials.
Glass JD, Benatar M, Polak M. Glass JD, et al. Among authors: benatar m. Neurology. 2007 May 1;68(18):1545-6; author reply 1546. doi: 10.1212/01.wnl.0000265319.46474.f6. Neurology. 2007. PMID: 17470765 No abstract available.
Towards a neuroimaging biomarker for amyotrophic lateral sclerosis.
Turner MR, Grosskreutz J, Kassubek J, Abrahams S, Agosta F, Benatar M, Filippi M, Goldstein LH, van den Heuvel M, Kalra S, Lulé D, Mohammadi B; first Neuroimaging Symosium in ALS (NISALS). Turner MR, et al. Among authors: benatar m. Lancet Neurol. 2011 May;10(5):400-3. doi: 10.1016/S1474-4422(11)70049-7. Lancet Neurol. 2011. PMID: 21511189 No abstract available.
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Renton AE, Majounie E, Waite A, Simón-Sánchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, Kalimo H, Paetau A, Abramzon Y, Remes AM, Kaganovich A, Scholz SW, Duckworth J, Ding J, Harmer DW, Hernandez DG, Johnson JO, Mok K, Ryten M, Trabzuni D, Guerreiro RJ, Orrell RW, Neal J, Murray A, Pearson J, Jansen IE, Sondervan D, Seelaar H, Blake D, Young K, Halliwell N, Callister JB, Toulson G, Richardson A, Gerhard A, Snowden J, Mann D, Neary D, Nalls MA, Peuralinna T, Jansson L, Isoviita VM, Kaivorinne AL, Hölttä-Vuori M, Ikonen E, Sulkava R, Benatar M, Wuu J, Chiò A, Restagno G, Borghero G, Sabatelli M; ITALSGEN Consortium; Heckerman D, Rogaeva E, Zinman L, Rothstein JD, Sendtner M, Drepper C, Eichler EE, Alkan C, Abdullaev Z, Pack SD, Dutra A, Pak E, Hardy J, Singleton A, Williams NM, Heutink P, Pickering-Brown S, Morris HR, Tienari PJ, Traynor BJ. Renton AE, et al. Among authors: benatar m. Neuron. 2011 Oct 20;72(2):257-68. doi: 10.1016/j.neuron.2011.09.010. Epub 2011 Sep 21. Neuron. 2011. PMID: 21944779 Free PMC article.
Controversies and priorities in amyotrophic lateral sclerosis.
Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, Traynor BJ, Van den Berg LH, Veldink JH, Vucic S, Kiernan MC. Turner MR, et al. Among authors: benatar m. Lancet Neurol. 2013 Mar;12(3):310-22. doi: 10.1016/S1474-4422(13)70036-X. Lancet Neurol. 2013. PMID: 23415570 Free PMC article. Review.
A case of familial ALS due to multi-system proteinopathy 1 and Huntington disease.
Oskarsson B, Wheelock V, Benatar M, Taylor JP, Joyce N, Chesak D, Jin LW. Oskarsson B, et al. Among authors: benatar m. Amyotroph Lateral Scler Frontotemporal Degener. 2015 Mar;16(1-2):124-6. doi: 10.3109/21678421.2014.952238. Epub 2014 Sep 10. Amyotroph Lateral Scler Frontotemporal Degener. 2015. PMID: 25205077 Free PMC article. No abstract available.
Progress towards a neuroimaging biomarker for amyotrophic lateral sclerosis.
Filippi M, Agosta F, Grosskreutz J, Benatar M, Kassubek J, Verstraete E, Turner MR; Neuroimaging Society in ALS (NiSALS). Filippi M, et al. Among authors: benatar m. Lancet Neurol. 2015 Aug;14(8):786-788. doi: 10.1016/S1474-4422(15)00134-9. Lancet Neurol. 2015. PMID: 26194923 No abstract available.
281 results