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Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response.
Theusch E, Ting FY, Qin Y, Stevens K, Naidoo D, King SM, Yang N, Orr J, Han BY, Cyster JG, Chen YI, Rotter JI, Krauss RM, Medina MW. Theusch E, et al. Among authors: medina mw. bioRxiv [Preprint]. 2023 Jun 15:2023.06.14.544860. doi: 10.1101/2023.06.14.544860. bioRxiv. 2023. Update in: Genome Med. 2024 Jul 26;16(1):93. doi: 10.1186/s13073-024-01366-9 PMID: 37397985 Free PMC article. Updated. Preprint.
RHOA is a modulator of the cholesterol-lowering effects of statin.
Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. Medina MW, et al. PLoS Genet. 2012;8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166513 Free PMC article.
63 results