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131 results

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Page 1
PI3Kδ activation, IL-6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas.
Arribas AJ, Napoli S, Gaudio E, Herbaux C, Cannas E, Tarantelli C, Bordone-Pittau R, Cascione L, Munz N, Aresu L, Sgrignani J, Rinaldi A, Kwee I, Rossi D, Cavalli A, Zucca E, Stussi G, Stathis A, Sloss C, Davids MS, Bertoni F. Arribas AJ, et al. Among authors: cascione l. Blood Adv. 2024 Dec 24;8(24):6268-6281. doi: 10.1182/bloodadvances.2023012291. Blood Adv. 2024. PMID: 39374583
Direct toll-like receptor triggering in colorectal cancer-associated stromal cells elicits immunostimulatory properties leading to enhanced immune cell recruitment.
Djordjevic J, Cisneros Romero NS, Cascione L, Mele V, Cremonesi E, Sorrenti E, Basso C, Villa M, Cianfarani A, Roesel R, Galafassi J, Majno-Hurst PE, Spagnoli G, Christoforidis D, Iezzi G. Djordjevic J, et al. Among authors: cascione l. Gut. 2024 Aug 8:gutjnl-2023-331759. doi: 10.1136/gutjnl-2023-331759. Online ahead of print. Gut. 2024. PMID: 39122362 Free article. No abstract available.
Targeting CD25+ lymphoma cells with the antibody-drug conjugate camidanlumab tesirine as a single agent or in combination with targeted agents.
Spriano F, Tarantelli C, Cascione L, Gaudio E, Golino G, Scalise L, Cacciapuoti MT, Zucca E, Stathis A, Van Berkel PH, Inghirami G, Zammarchi F, Bertoni F. Spriano F, et al. Among authors: cascione l. Br J Haematol. 2024 Nov;205(5):1873-1882. doi: 10.1111/bjh.19658. Epub 2024 Jul 30. Br J Haematol. 2024. PMID: 39080847
DiGAS: Differential gene allele spectrum as a descriptor in genetic studies.
Aparo A, Bonnici V, Avesani S, Cascione L, Giugno R; Alzheimer’s Disease Neuroimaging Initiative. Aparo A, et al. Among authors: cascione l. Comput Biol Med. 2024 Sep;179:108924. doi: 10.1016/j.compbiomed.2024.108924. Epub 2024 Jul 26. Comput Biol Med. 2024. PMID: 39067286 Free article.
Transcriptomic signature of stress-induced premature senescence in cardiomyocytes.
Rendon-Angel A, Lazzarini E, Cascione L, Burrello J, Goshovska Y, Biemmi V, Panella S, Bolis S, Colucci M, Altomare C, Rinaldi A, Torre T, Alimonti A, Barile L. Rendon-Angel A, et al. Among authors: cascione l. Vascul Pharmacol. 2024 Jun;155:107342. doi: 10.1016/j.vph.2024.107342. Vascul Pharmacol. 2024. PMID: 38985620 No abstract available.
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.
Spriano F, Sartori G, Sgrignani J, Barnabei L, Arribas AJ, Guala M, Del Amor AMC, Tomasso MR, Tarantelli C, Cascione L, Golino G, Riveiro ME, Bortolozzi R, Lupia A, Paduano F, Huguet S, Rezai K, Rinaldi A, Margheriti F, Ventura P, Guarda G, Costa G, Rocca R, Furlan A, Verdonk LM, Innocenti P, Martin NI, Viola G, Driessen C, Zucca E, Stathis A, Gahtory D, Van den Nieuwboer M, Bornhauser B, Alcaro S, Trapasso F, Cristobal S, Padrick SB, Pazzi N, Cavalli F, Cavalli A, Gaudio E, Bertoni F. Spriano F, et al. Among authors: cascione l. Haematologica. 2024 Nov 1;109(11):3602-3614. doi: 10.3324/haematol.2022.282672. Haematologica. 2024. PMID: 38899342 Free PMC article.
Extracellular Vesicle - MDM2-DNA as a Potential Liquid Biopsy Biomarker for Disease Identification in Retroperitoneal Liposarcoma.
Calore F, Casadei L, Sarchet PD, Fadda P, Nigita G, Coombes KR, Cascione L, Costas C de Faria F, Tahara S, Iwenofu OH, Pollock RE, Grignol VP. Calore F, et al. Among authors: cascione l. Ann Surg. 2024 May 21:10.1097/SLA.0000000000006345. doi: 10.1097/SLA.0000000000006345. Online ahead of print. Ann Surg. 2024. PMID: 38771951
Targeting CD19-positive lymphomas with the antibodydrug conjugate loncastuximab tesirine: preclinical evidence of activity as a single agent and in combination therapy.
Tarantelli C, Wald D, Munz N, Spriano F, Bruscaggin A, Cannas E, Cascione L, Gaudio E, Arribas AJ, Manjappa S, Golino G, Scalise L, Cacciapuoti MT, Zucca E, Stathis A, Inghirami G, Van Berkel PH, Rossi D, Caimi PF, Zammarchi F, Bertoni F. Tarantelli C, et al. Among authors: cascione l. Haematologica. 2024 Oct 1;109(10):3314-3326. doi: 10.3324/haematol.2023.284197. Haematologica. 2024. PMID: 38721745 Free PMC article.
Circulating microRNA Analysis in a Prospective Co-clinical Trial Identifies MIR652-3p as a Response Biomarker and Driver of Regorafenib Resistance Mechanisms in Colorectal Cancer.
Hedayat S, Cascione L, Cunningham D, Schirripa M, Lampis A, Hahne JC, Tunariu N, Hong SP, Marchetti S, Khan K, Fontana E, Angerilli V, Delrieux M, Nava Rodrigues D, Procaccio L, Rao S, Watkins D, Starling N, Chau I, Braconi C, Fotiadis N, Begum R, Guppy N, Howell L, Valenti M, Cribbes S, Kolozsvari B, Kirkin V, Lonardi S, Ghidini M, Passalacqua R, Elghadi R, Magnani L, Pinato DJ, Di Maggio F, Ghelardi F, Sottotetti E, Vetere G, Ciracì P, Vlachogiannis G, Pietrantonio F, Cremolini C, Cortellini A, Loupakis F, Fassan M, Valeri N. Hedayat S, et al. Among authors: cascione l. Clin Cancer Res. 2024 May 15;30(10):2140-2159. doi: 10.1158/1078-0432.CCR-23-2748. Clin Cancer Res. 2024. PMID: 38376926 Clinical Trial.
ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies.
Zammarchi F, Havenith KE, Sachini N, Janghra N, Chivers S, Idusogie E, Gaudio E, Tarantelli C, Bertelli F, Santos K, Tyrer P, Corbett S, Spriano F, Golino G, Cascione L, Bertoni F, Hartley JA, van Berkel PH. Zammarchi F, et al. Among authors: cascione l. Mol Cancer Ther. 2024 Apr 2;23(4):520-531. doi: 10.1158/1535-7163.MCT-23-0506. Mol Cancer Ther. 2024. PMID: 38324336 Free PMC article.
131 results