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CTC-177, a novel drug-Fc conjugate, shows promise as an immunoprophylactic agent against multidrug-resistant Gram-negative bacterial infections.
Lovey A, Lee A, Yu A, Krel M, Wang M, Paderu P, Brady T, Hough G, Zhao Q, Balkovec JM, Perlin DS, Zhao Y. Lovey A, et al. Among authors: zhao y, zhao q. JAC Antimicrob Resist. 2024 Jul 26;6(4):dlae100. doi: 10.1093/jacamr/dlae100. eCollection 2024 Aug. JAC Antimicrob Resist. 2024. PMID: 39071163 Free PMC article.
Development of Novel Immunoprophylactic Agents against Multidrug-Resistant Gram-Negative Bacterial Infections.
Lovey A, Krel M, Borchardt A, Brady T, Cole JN, Do QQ, Fortier J, Hough G, Jiang W, Noncovich A, Tari L, Zhao Q, Balkovec JM, Zhao Y, Perlin DS. Lovey A, et al. Among authors: zhao y, zhao q. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0098521. doi: 10.1128/AAC.00985-21. Epub 2021 Aug 9. Antimicrob Agents Chemother. 2021. PMID: 34370589 Free PMC article.
CD101: a novel long-acting echinocandin.
Zhao Y, Perez WB, Jiménez-Ortigosa C, Hough G, Locke JB, Ong V, Bartizal K, Perlin DS. Zhao Y, et al. Cell Microbiol. 2016 Sep;18(9):1308-16. doi: 10.1111/cmi.12640. Epub 2016 Jul 22. Cell Microbiol. 2016. PMID: 27354115 Free PMC article.
Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis.
Zhao Y, Lee MH, Paderu P, Lee A, Jimenez-Ortigosa C, Park S, Mansbach RS, Shaw KJ, Perlin DS. Zhao Y, et al. Antimicrob Agents Chemother. 2018 Sep 24;62(10):e00425-18. doi: 10.1128/AAC.00425-18. Print 2018 Oct. Antimicrob Agents Chemother. 2018. PMID: 30012766 Free PMC article.
Update on Antifungal Drug Resistance.
Perlin DS, Shor E, Zhao Y. Perlin DS, et al. Among authors: zhao y. Curr Clin Microbiol Rep. 2015 Jun 1;2(2):84-95. doi: 10.1007/s40588-015-0015-1. Curr Clin Microbiol Rep. 2015. PMID: 26120512 Free PMC article.
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