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AZD2693, a PNPLA3 antisense oligonucleotide, for the treatment of MASH in 148M homozygous participants: two randomized phase I trials.
Armisen J, Rauschecker M, Sarv J, Liljeblad M, Wernevik L, Niazi M, Knöchel J, Eklund O, Sandell T, Sherwood J, Bergenholm L, Hallén S, Wang S, Kamble P, Bhat M, Maxvall I, Wang Y, Lee RG, Bhanot S, Guo S, Romeo S, Lawitz E, Fjellström O, Lindén D, Blau JE, Loomba R. Armisen J, et al. Among authors: guo s. J Hepatol. 2025 Jan 9:S0168-8278(25)00003-0. doi: 10.1016/j.jhep.2024.12.046. Online ahead of print. J Hepatol. 2025. PMID: 39798707 Free article.
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