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Page 1
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.
van den Berg M, Shi Z, Claassen WJ, Hooijman P, Lewis CTA, Andersen JL, van der Pijl RJ, Bogaards SJP, Conijn S, Peters EL, Begthel LPL, Uijterwijk B, Lindqvist J, Langlais PR, Girbes ARJ, Stapel S, Granzier H, Campbell KS, Ma W, Irving T, Hwee DT, Hartman JJ, Malik FI, Paul M, Beishuizen A, Ochala J, Heunks L, Ottenheijm CAC. van den Berg M, et al. Among authors: hooijman p. Sci Transl Med. 2024 Jul 31;16(758):eadg3894. doi: 10.1126/scitranslmed.adg3894. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083588
Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator.
van der Pijl RJ, van den Berg M, van de Locht M, Shen S, Bogaards SJP, Conijn S, Langlais P, Hooijman PE, Labeit S, Heunks LMA, Granzier H, Ottenheijm CAC. van der Pijl RJ, et al. Among authors: hooijman pe. J Gen Physiol. 2021 Jul 5;153(7):e202112925. doi: 10.1085/jgp.202112925. Epub 2021 Jun 21. J Gen Physiol. 2021. PMID: 34152365 Free PMC article.
Positive End-Expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers.
Lindqvist J, van den Berg M, van der Pijl R, Hooijman PE, Beishuizen A, Elshof J, de Waard M, Girbes A, Spoelstra-de Man A, Shi ZH, van den Brom C, Bogaards S, Shen S, Strom J, Granzier H, Kole J, Musters RJP, Paul MA, Heunks LMA, Ottenheijm CAC. Lindqvist J, et al. Among authors: hooijman pe. Am J Respir Crit Care Med. 2018 Aug 15;198(4):472-485. doi: 10.1164/rccm.201709-1917OC. Am J Respir Crit Care Med. 2018. PMID: 29578749 Free PMC article.
Diaphragm Atrophy and Weakness in the Absence of Mitochondrial Dysfunction in the Critically Ill.
van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC. van den Berg M, et al. Among authors: hooijman pe. Am J Respir Crit Care Med. 2017 Dec 15;196(12):1544-1558. doi: 10.1164/rccm.201703-0501OC. Am J Respir Crit Care Med. 2017. PMID: 28787181 Free PMC article.
Reduced force of diaphragm muscle fibers in patients with chronic thromboembolic pulmonary hypertension.
Manders E, Bonta PI, Kloek JJ, Symersky P, Bogaard HJ, Hooijman PE, Jasper JR, Malik FI, Stienen GJ, Vonk-Noordegraaf A, de Man FS, Ottenheijm CA. Manders E, et al. Among authors: hooijman pe. Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1;311(1):L20-8. doi: 10.1152/ajplung.00113.2016. Epub 2016 May 17. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27190061 Free PMC article.
Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients.
Hooijman PE, Beishuizen A, Witt CC, de Waard MC, Girbes AR, Spoelstra-de Man AM, Niessen HW, Manders E, van Hees HW, van den Brom CE, Silderhuis V, Lawlor MW, Labeit S, Stienen GJ, Hartemink KJ, Paul MA, Heunks LM, Ottenheijm CA. Hooijman PE, et al. Am J Respir Crit Care Med. 2015 May 15;191(10):1126-38. doi: 10.1164/rccm.201412-2214OC. Am J Respir Crit Care Med. 2015. PMID: 25760684 Free PMC article.
Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation.
Hooijman PE, Paul MA, Stienen GJ, Beishuizen A, Van Hees HW, Singhal S, Bashir M, Budak MT, Morgen J, Barsotti RJ, Levine S, Ottenheijm CA. Hooijman PE, et al. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15;307(6):L460-70. doi: 10.1152/ajplung.00076.2014. Epub 2014 Jul 18. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 25038190 Free PMC article. Clinical Trial.
Diaphragm fiber strength is reduced in critically ill patients and restored by a troponin activator.
Hooijman PE, Beishuizen A, de Waard MC, de Man FS, Vermeijden JW, Steenvoorde P, Bouwman RA, Lommen W, van Hees HW, Heunks LM, Dickhoff C, van der Peet DL, Girbes AR, Jasper JR, Malik FI, Stienen GJ, Hartemink KJ, Paul MA, Ottenheijm CA. Hooijman PE, et al. Am J Respir Crit Care Med. 2014 Apr 1;189(7):863-5. doi: 10.1164/rccm.201312-2260LE. Am J Respir Crit Care Med. 2014. PMID: 24684359 Free PMC article. No abstract available.
13 results