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Page 1
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.
van den Berg M, Shi Z, Claassen WJ, Hooijman P, Lewis CTA, Andersen JL, van der Pijl RJ, Bogaards SJP, Conijn S, Peters EL, Begthel LPL, Uijterwijk B, Lindqvist J, Langlais PR, Girbes ARJ, Stapel S, Granzier H, Campbell KS, Ma W, Irving T, Hwee DT, Hartman JJ, Malik FI, Paul M, Beishuizen A, Ochala J, Heunks L, Ottenheijm CAC. van den Berg M, et al. Among authors: lewis cta. Sci Transl Med. 2024 Jul 31;16(758):eadg3894. doi: 10.1126/scitranslmed.adg3894. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083588
Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption.
Lewis CTA, Tabrizian L, Nielsen J, Laitila J, Beck TN, Olsen MS, Ognjanovic MM, Aagaard P, Hokken R, Laugesen S, Ingersen A, Andersen JL, Soendenbroe C, Helge JW, Dela F, Larsen S, Sahl RE, Rømer T, Hansen MT, Frandsen J, Suetta C, Ochala J. Lewis CTA, et al. J Gen Physiol. 2023 Jul 3;155(7):e202213268. doi: 10.1085/jgp.202213268. Epub 2023 May 25. J Gen Physiol. 2023. PMID: 37227464 Free PMC article.
Remodeling of skeletal muscle myosin metabolic states in hibernating mammals.
Lewis CTA, Melhedegaard EG, Ognjanovic MM, Olsen MS, Laitila J, Seaborne RAE, Gronset M, Zhang C, Iwamoto H, Hessel AL, Kuehn MN, Merino C, Amigo N, Frobert O, Giroud S, Staples JF, Goropashnaya AV, Fedorov VB, Barnes B, Toien O, Drew K, Sprenger RJ, Ochala J. Lewis CTA, et al. Elife. 2024 May 16;13:RP94616. doi: 10.7554/eLife.94616. Elife. 2024. PMID: 38752835 Free PMC article.
CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle.
Negoita F, Addinsall AB, Hellberg K, Bringas CF, Hafen PS, Sermersheim TJ, Agerholm M, Lewis CTA, Ahwazi D, Ling NXY, Larsen JK, Deshmukh AS, Hossain MA, Oakhill JS, Ochala J, Brault JJ, Sankar U, Drewry DH, Scott JW, Witczak CA, Sakamoto K. Negoita F, et al. Among authors: lewis cta. Mol Metab. 2023 Sep;75:101761. doi: 10.1016/j.molmet.2023.101761. Epub 2023 Jun 26. Mol Metab. 2023. PMID: 37380024 Free PMC article.
Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals.
Lewis CTA, Melhedegaard EG, Ognjanovic MM, Olsen MS, Laitila J, Seaborne RAE, Gronset MN, Zhang C, Iwamoto H, Hessel AL, Kuehn MN, Merino C, Amigo N, Frobert O, Giroud S, Staples JF, Goropashnaya AV, Fedorov VB, Barnes BM, Toien O, Drew KL, Sprenger RJ, Ochala J. Lewis CTA, et al. bioRxiv [Preprint]. 2024 Feb 27:2023.11.14.566992. doi: 10.1101/2023.11.14.566992. bioRxiv. 2024. Update in: Elife. 2024 May 16;13:RP94616. doi: 10.7554/eLife.94616 PMID: 38014200 Free PMC article. Updated. Preprint.
The elephant in the inbox.
Lewis CTA. Lewis CTA. Science. 2022 Nov 18;378(6621):719. doi: 10.1126/science.adf5850. Epub 2022 Nov 17. Science. 2022. PMID: 36395237 No abstract available.