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Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.
van den Berg M, Shi Z, Claassen WJ, Hooijman P, Lewis CTA, Andersen JL, van der Pijl RJ, Bogaards SJP, Conijn S, Peters EL, Begthel LPL, Uijterwijk B, Lindqvist J, Langlais PR, Girbes ARJ, Stapel S, Granzier H, Campbell KS, Ma W, Irving T, Hwee DT, Hartman JJ, Malik FI, Paul M, Beishuizen A, Ochala J, Heunks L, Ottenheijm CAC. van den Berg M, et al. Among authors: ottenheijm cac. Sci Transl Med. 2024 Jul 31;16(758):eadg3894. doi: 10.1126/scitranslmed.adg3894. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083588
Titin and diaphragm dysfunction in mechanically ventilated rats.
van Hees HW, Schellekens WJ, Andrade Acuña GL, Linkels M, Hafmans T, Ottenheijm CA, Granzier HL, Scheffer GJ, van der Hoeven JG, Dekhuijzen PN, Heunks LM. van Hees HW, et al. Intensive Care Med. 2012 Apr;38(4):702-9. doi: 10.1007/s00134-012-2504-5. Epub 2012 Feb 11. Intensive Care Med. 2012. PMID: 22327561 Free PMC article.
Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation.
Hooijman PE, Paul MA, Stienen GJ, Beishuizen A, Van Hees HW, Singhal S, Bashir M, Budak MT, Morgen J, Barsotti RJ, Levine S, Ottenheijm CA. Hooijman PE, et al. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15;307(6):L460-70. doi: 10.1152/ajplung.00076.2014. Epub 2014 Jul 18. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 25038190 Free PMC article. Clinical Trial.
Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients.
Hooijman PE, Beishuizen A, Witt CC, de Waard MC, Girbes AR, Spoelstra-de Man AM, Niessen HW, Manders E, van Hees HW, van den Brom CE, Silderhuis V, Lawlor MW, Labeit S, Stienen GJ, Hartemink KJ, Paul MA, Heunks LM, Ottenheijm CA. Hooijman PE, et al. Am J Respir Crit Care Med. 2015 May 15;191(10):1126-38. doi: 10.1164/rccm.201412-2214OC. Am J Respir Crit Care Med. 2015. PMID: 25760684 Free PMC article.
138 results