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Page 1
Predictability of antigen binding based on short motifs in the antibody CDRH3.
Scheffer L, Reber EE, Mehta BB, Pavlović M, Chernigovskaya M, Richardson E, Akbar R, Lund-Johansen F, Greiff V, Haff IH, Sandve GK. Scheffer L, et al. Among authors: chernigovskaya m. Brief Bioinform. 2024 Sep 23;25(6):bbae537. doi: 10.1093/bib/bbae537. Brief Bioinform. 2024. PMID: 39438077 Free PMC article.
Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability.
Bashour H, Smorodina E, Pariset M, Zhong J, Akbar R, Chernigovskaya M, Lê Quý K, Snapkow I, Rawat P, Krawczyk K, Sandve GK, Gutierrez-Marcos J, Gutierrez DN, Andersen JT, Greiff V. Bashour H, et al. Among authors: chernigovskaya m. Commun Biol. 2024 Jul 31;7(1):922. doi: 10.1038/s42003-024-06561-3. Commun Biol. 2024. PMID: 39085379 Free PMC article.
Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling.
Lê Quý K, Chernigovskaya M, Stensland M, Singh S, Leem J, Revale S, Yadin DA, Nice FL, Povall C, Minns DH, Galson JD, Nyman TA, Snapkow I, Greiff V. Lê Quý K, et al. Among authors: chernigovskaya m. NPJ Syst Biol Appl. 2024 Jul 12;10(1):73. doi: 10.1038/s41540-024-00402-z. NPJ Syst Biol Appl. 2024. PMID: 38997321 Free PMC article.
Application and challenges of TCR and BCR sequencing to investigate T- and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm.
Elster C, Ommer-Bläsius M, Lang A, Vajen T, Pfeiler S, Feige M, Yau Pang T, Böttenberg M, Verheyen S, Lê Quý K, Chernigovskaya M, Kelm M, Winkels H, Schmidt SV, Greiff V, Gerdes N. Elster C, et al. Among authors: chernigovskaya m. Front Cardiovasc Med. 2023 Nov 14;10:1221620. doi: 10.3389/fcvm.2023.1221620. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 38034381 Free PMC article.
Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for antibody specificity prediction.
Robert PA, Akbar R, Frank R, Pavlović M, Widrich M, Snapkov I, Slabodkin A, Chernigovskaya M, Scheffer L, Smorodina E, Rawat P, Mehta BB, Vu MH, Mathisen IF, Prósz A, Abram K, Olar A, Miho E, Haug DTT, Lund-Johansen F, Hochreiter S, Haff IH, Klambauer G, Sandve GK, Greiff V. Robert PA, et al. Among authors: chernigovskaya m. Nat Comput Sci. 2022 Dec;2(12):845-865. doi: 10.1038/s43588-022-00372-4. Epub 2022 Dec 19. Nat Comput Sci. 2022. PMID: 38177393
In silico proof of principle of machine learning-based antibody design at unconstrained scale.
Akbar R, Robert PA, Weber CR, Widrich M, Frank R, Pavlović M, Scheffer L, Chernigovskaya M, Snapkov I, Slabodkin A, Mehta BB, Miho E, Lund-Johansen F, Andersen JT, Hochreiter S, Hobæk Haff I, Klambauer G, Sandve GK, Greiff V. Akbar R, et al. Among authors: chernigovskaya m. MAbs. 2022 Jan-Dec;14(1):2031482. doi: 10.1080/19420862.2022.2031482. MAbs. 2022. PMID: 35377271 Free PMC article.
Individualized VDJ recombination predisposes the available Ig sequence space.
Slabodkin A, Chernigovskaya M, Mikocziova I, Akbar R, Scheffer L, Pavlović M, Bashour H, Snapkov I, Mehta BB, Weber CR, Gutierrez-Marcos J, Sollid LM, Haff IH, Sandve GK, Robert PA, Greiff V. Slabodkin A, et al. Among authors: chernigovskaya m. Genome Res. 2021 Dec;31(12):2209-2224. doi: 10.1101/gr.275373.121. Epub 2021 Nov 23. Genome Res. 2021. PMID: 34815307 Free PMC article.
13 results