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Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis.
Wathieu C, Lavergne A, Xu X, Rolot M, Nemazanyy I, Shostak K, El Hachem N, Maurizy C, Leemans C, Close P, Nguyen L, Desmet C, Tielens S, Dewals BG, Chariot A. Wathieu C, et al. Among authors: shostak k. EMBO J. 2024 Sep;43(18):3916-3947. doi: 10.1038/s44318-024-00184-4. Epub 2024 Jul 31. EMBO J. 2024. PMID: 39085648 Free PMC article.
BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.
Keutgens A, Zhang X, Shostak K, Robert I, Olivier S, Vanderplasschen A, Chapelle JP, Viatour P, Merville MP, Bex F, Gothot A, Chariot A. Keutgens A, et al. Among authors: shostak k. J Biol Chem. 2010 Aug 13;285(33):25831-40. doi: 10.1074/jbc.M110.112128. Epub 2010 Jun 17. J Biol Chem. 2010. PMID: 20558726 Free PMC article.
NF-κB-induced KIAA1199 promotes survival through EGFR signalling.
Shostak K, Zhang X, Hubert P, Göktuna SI, Jiang Z, Klevernic I, Hildebrand J, Roncarati P, Hennuy B, Ladang A, Somja J, Gothot A, Close P, Delvenne P, Chariot A. Shostak K, et al. Nat Commun. 2014 Nov 4;5:5232. doi: 10.1038/ncomms6232. Nat Commun. 2014. PMID: 25366117 Free PMC article.
A role for APPL1 in TLR3/4-dependent TBK1 and IKKε activation in macrophages.
Chau TL, Göktuna SI, Rammal A, Casanova T, Duong HQ, Gatot JS, Close P, Dejardin E, Desmecht D, Shostak K, Chariot A. Chau TL, et al. Among authors: shostak k. J Immunol. 2015 Apr 15;194(8):3970-83. doi: 10.4049/jimmunol.1401614. Epub 2015 Mar 16. J Immunol. 2015. PMID: 25780039
EGFR and NF-κB: partners in cancer.
Shostak K, Chariot A. Shostak K, et al. Trends Mol Med. 2015 Jun;21(6):385-93. doi: 10.1016/j.molmed.2015.04.001. Epub 2015 May 13. Trends Mol Med. 2015. PMID: 25979753 Free article. Review.
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.
Ladang A, Rapino F, Heukamp LC, Tharun L, Shostak K, Hermand D, Delaunay S, Klevernic I, Jiang Z, Jacques N, Jamart D, Migeot V, Florin A, Göktuna S, Malgrange B, Sansom OJ, Nguyen L, Büttner R, Close P, Chariot A. Ladang A, et al. Among authors: shostak k. J Exp Med. 2015 Nov 16;212(12):2057-75. doi: 10.1084/jem.20142288. Epub 2015 Nov 2. J Exp Med. 2015. PMID: 26527802 Free PMC article.
44 results