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Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.
Tarullo M, Fernandez Rodriguez G, Iaiza A, Venezia S, Macone A, Incocciati A, Masciarelli S, Marchioni M, Giorgis M, Lolli ML, Fornaseri F, Proietti L, Grebien F, Rosignoli S, Paiardini A, Rotili D, Mai A, Bochenkova E, Caflisch A, Fazi F, Fatica A. Tarullo M, et al. ACS Pharmacol Transl Sci. 2024 Nov 26;7(12):4096-4111. doi: 10.1021/acsptsci.4c00533. eCollection 2024 Dec 13. ACS Pharmacol Transl Sci. 2024. PMID: 39698280
Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3.
Cesaro B, Iaiza A, Piscopo F, Tarullo M, Cesari E, Rotili D, Mai A, Diana A, Londero M, Del Giacco L, Masetti R, Di Leone A, Naro C, Masciarelli S, Fontemaggi G, Sette C, Fazi F, Fatica A. Cesaro B, et al. Among authors: tarullo m. Cancer Commun (Lond). 2024 Feb;44(2):282-286. doi: 10.1002/cac2.12509. Epub 2023 Dec 15. Cancer Commun (Lond). 2024. PMID: 38102821 Free PMC article. No abstract available.
Regulation of Gene Expression by m6Am RNA Modification.
Cesaro B, Tarullo M, Fatica A. Cesaro B, et al. Among authors: tarullo m. Int J Mol Sci. 2023 Jan 23;24(3):2277. doi: 10.3390/ijms24032277. Int J Mol Sci. 2023. PMID: 36768600 Free PMC article. Review.