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Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis.
Kearney AL, Norris DM, Ghomlaghi M, Kin Lok Wong M, Humphrey SJ, Carroll L, Yang G, Cooke KC, Yang P, Geddes TA, Shin S, Fazakerley DJ, Nguyen LK, James DE, Burchfield JG. Kearney AL, et al. Among authors: ghomlaghi m. Elife. 2021 Jul 13;10:e66942. doi: 10.7554/eLife.66942. Elife. 2021. PMID: 34253290 Free PMC article.