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Page 1
Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Jena KK, Mambu J, Boehmer D, Sposito B, Millet V, de Sousa Casal J, Muendlein HI, Spreafico R, Fenouil R, Spinelli L, Wurbel S, Riquier C, Galland F, Naquet P, Chasson L, Elkins M, Mitsialis V, Ketelut-Carneiro N, Bugda Gwilt K, Thiagarajah JR, Ruan HB, Lin Z, Lien E, Shao F, Chou J, Poltorak A, Ordovas-Montanes J, Fitzgerald KA, Snapper SB, Broggi A, Zanoni I. Jena KK, et al. Among authors: ordovas montanes j. Cell. 2024 Dec 26;187(26):7533-7550.e23. doi: 10.1016/j.cell.2024.10.010. Epub 2024 Nov 4. Cell. 2024. PMID: 39500322
The choroid plexus synergizes with immune cells during neuroinflammation.
Xu H, Lotfy P, Gelb S, Pragana A, Hehnly C, Byer LIJ, Shipley FB, Zawadzki ME, Cui J, Deng L, Taylor M, Webb M, Lidov HGW, Andermann ML, Chiu IM, Ordovas-Montanes J, Lehtinen MK. Xu H, et al. Among authors: ordovas montanes j. Cell. 2024 Sep 5;187(18):4946-4963.e17. doi: 10.1016/j.cell.2024.07.002. Epub 2024 Jul 31. Cell. 2024. PMID: 39089253 Free article.
Primary nasal influenza infection rewires tissue-scale memory response dynamics.
Kazer SW, Match CM, Langan EM, Messou MA, LaSalle TJ, O'Leary E, Marbourg J, Naughton K, von Andrian UH, Ordovas-Montanes J. Kazer SW, et al. Among authors: ordovas montanes j. Immunity. 2024 Aug 13;57(8):1955-1974.e8. doi: 10.1016/j.immuni.2024.06.005. Epub 2024 Jul 3. Immunity. 2024. PMID: 38964332
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection.
Ziegler CGK, Owings AH, Galeas-Pena M, Kazer SW, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Diamond G, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: ordovas montanes j. Microbiol Spectr. 2024 Jun 4;12(6):e0351623. doi: 10.1128/spectrum.03516-23. Epub 2024 Apr 30. Microbiol Spectr. 2024. PMID: 38687064 Free PMC article.
Primary nasal viral infection rewires the tissue-scale memory response.
Kazer SW, Match CM, Langan EM, Messou MA, LaSalle TJ, O'Leary E, Marbourg J, Naughton K, von Andrian UH, Ordovas-Montanes J. Kazer SW, et al. Among authors: ordovas montanes j. bioRxiv [Preprint]. 2024 Mar 18:2023.05.11.539887. doi: 10.1101/2023.05.11.539887. bioRxiv. 2024. Update in: Immunity. 2024 Aug 13;57(8):1955-1974.e8. doi: 10.1016/j.immuni.2024.06.005 PMID: 38562902 Free PMC article. Updated. Preprint.
Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infection.
Tomalka JA, Owings A, Galeas-Pena M, Ziegler CGK, Robinson TO, Wichman TG, Laird H, Williams HB, Dhaliwal NS, Everman S, Zafar Y, Shalek AK, Horwitz BH, Ordovas-Montanes J, Glover SC, Gibert Y. Tomalka JA, et al. Among authors: ordovas montanes j. medRxiv [Preprint]. 2023 Sep 15:2023.09.14.23295549. doi: 10.1101/2023.09.14.23295549. medRxiv. 2023. PMID: 37745424 Free PMC article. Preprint.
A collaboration between immune cells and the choroid plexus epithelium in brain inflammation.
Xu H, Lotfy P, Gelb S, Pragana A, Hehnly C, Shipley FB, Zawadzki ME, Cui J, Deng L, Taylor M, Webb M, Lidov HGW, Andermann ML, Chiu IM, Ordovas-Montanes J, Lehtinen MK. Xu H, et al. Among authors: ordovas montanes j. bioRxiv [Preprint]. 2023 Aug 8:2023.08.07.552298. doi: 10.1101/2023.08.07.552298. bioRxiv. 2023. PMID: 37609192 Free PMC article. Preprint.
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases.
Weeks EM, Ulirsch JC, Cheng NY, Trippe BL, Fine RS, Miao J, Patwardhan TA, Kanai M, Nasser J, Fulco CP, Tashman KC, Aguet F, Li T, Ordovas-Montanes J, Smillie CS, Biton M, Shalek AK, Ananthakrishnan AN, Xavier RJ, Regev A, Gupta RM, Lage K, Ardlie KG, Hirschhorn JN, Lander ES, Engreitz JM, Finucane HK. Weeks EM, et al. Among authors: ordovas montanes j. Nat Genet. 2023 Aug;55(8):1267-1276. doi: 10.1038/s41588-023-01443-6. Epub 2023 Jul 13. Nat Genet. 2023. PMID: 37443254 Free PMC article.
57 results