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Page 1
Computationally designed mRNA-launched protein nanoparticle vaccines.
Hendricks GG, Grigoryan L, Navarro MJ, Catanzaro NJ, Hubbard ML, Powers JM, Mattocks M, Treichel C, Walls AC, Lee J, Ellis D, Wang JYJ, Cheng S, Miranda MC, Valdez A, Chao CW, Chan S, Men C, Johnson MR, Hui H, Wu SY, Lujan V, Muramatsu H, Lin PJC, Sung MMH, Tam YK, Leaf EM, Pardi N, Baric RS, Pulendran B, Veesler D, Schäfer A, King NP. Hendricks GG, et al. Among authors: tam yk. bioRxiv [Preprint]. 2024 Jul 23:2024.07.22.604655. doi: 10.1101/2024.07.22.604655. bioRxiv. 2024. PMID: 39091730 Free PMC article. Preprint.
Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
Malewana RD, Stalls V, May A, Lu X, Martinez DR, Schäfer A, Li D, Barr M, Sutherland LL, Lee E, Parks R, Beck WE, Newman A, Bock KW, Minai M, Nagata BM, DeMarco CT, Denny TN, Oguin TH 3rd, Rountree W, Wang Y, Mansouri K, Edwards RJ, Sempowski GD, Eaton A, Muramatsu H, Henderson R, Tam Y, Barbosa C, Tang J, Cain DW, Santra S, Moore IN, Andersen H, Lewis MG, Golding H, Seder R, Khurana S, Montefiori DC, Pardi N, Weissman D, Baric RS, Acharya P, Haynes BF, Saunders KO. Malewana RD, et al. bioRxiv [Preprint]. 2023 Dec 19:2023.12.18.572191. doi: 10.1101/2023.12.18.572191. bioRxiv. 2023. PMID: 38187726 Free PMC article. Preprint.
Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy to treat murine liver diseases.
Smith AR, Rizvi F, Everton E, Adeagbo A, Wu S, Tam Y, Muramatsu H, Pardi N, Weissman D, Gouon-Evans V. Smith AR, et al. bioRxiv [Preprint]. 2024 Jan 11:2024.01.11.575286. doi: 10.1101/2024.01.11.575286. bioRxiv. 2024. Update in: Nat Commun. 2024 Jun 12;15(1):5010. doi: 10.1038/s41467-024-49332-8 PMID: 38260488 Free PMC article. Updated. Preprint.
Distinct components of nucleoside-modified messenger RNA vaccines cooperate to instruct efficient germinal center responses.
Bettini E, Chudnovskiy A, Protti G, Nakadakari-Higa S, Ceglia S, Castaño D, Chiu J, Muramatsu H, Mdluli T, Abraham E, Lipinszki Z, Maillard I, Tam YK, Reboldi A, Pardi N, Spreafico R, Victora GD, Locci M. Bettini E, et al. Among authors: tam yk. bioRxiv [Preprint]. 2024 May 17:2024.05.17.594726. doi: 10.1101/2024.05.17.594726. bioRxiv. 2024. PMID: 38798523 Free PMC article. Preprint.
An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.
Castruccio Castracani C, Breda L, Papp TE, Guerra A, Radaelli E, Assenmacher CA, Finesso G, Mui BL, Tam YK, Fontana S, Riganti C, Fiorito V, Petrillo S, Tolosano E, Parhiz H, Rivella S. Castruccio Castracani C, et al. Among authors: tam yk. Blood. 2024 Dec 10:blood.2024025846. doi: 10.1182/blood.2024025846. Online ahead of print. Blood. 2024. PMID: 39656107
Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire.
Abt ER, Lam AK, Noguchi M, Rashid K, McLaughlin J, Teng PL, Tran W, Cheng D, Nesterenko PA, Mao Z, Creech AL, Burton Sojo G, Jeyachandran AV, Tam YK, Henley JE, Comai L, Pardi N, Arumugaswami V, Witte ON, Radu CG, Wu TT. Abt ER, et al. Among authors: tam yk. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2406332121. doi: 10.1073/pnas.2406332121. Epub 2024 Nov 26. Proc Natl Acad Sci U S A. 2024. PMID: 39589869 Free PMC article.
Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection.
Atochina-Vasserman EN, Lindesmith LC, Mirabelli C, Ona NA, Reagan EK, Brewer-Jensen PD, Mercado-Lopez X, Shahnawaz H, Meshanni JA, Baboo I, Mallory ML, Zweigart MR, May SR, Mui BL, Tam YK, Wobus CE, Baric RS, Weissman D. Atochina-Vasserman EN, et al. Among authors: tam yk. NPJ Vaccines. 2024 Oct 1;9(1):182. doi: 10.1038/s41541-024-00976-z. NPJ Vaccines. 2024. PMID: 39353926 Free PMC article.
Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy.
Chappell ME, Breda L, Tricoli L, Guerra A, Jarocha D, Castruccio Castracani C, Papp TE, Tanaka N, Hamilton N, Triebwasser MP, Ghiaccio V, Fedorky MT, Gollomp KL, Bochenek V, Roche AM, Everett JK, Cook EJ, Bushman FD, Teawtrakul N, Glentis S, Kattamis A, Mui BL, Tam YK, Weissman D, Abdulmalik O, Parhiz H, Rivella S. Chappell ME, et al. Among authors: tam yk. Blood. 2024 Oct 10;144(15):1633-1645. doi: 10.1182/blood.2023023349. Blood. 2024. PMID: 38949981
Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction.
Wiehe K, Saunders KO, Stalls V, Cain DW, Venkatayogi S, Martin Beem JS, Berry M, Evangelous T, Henderson R, Hora B, Xia SM, Jiang C, Newman A, Bowman C, Lu X, Bryan ME, Bal J, Sanzone A, Chen H, Eaton A, Tomai MA, Fox CB, Tam YK, Barbosa C, Bonsignori M, Muramatsu H, Alam SM, Montefiori DC, Williams WB, Pardi N, Tian M, Weissman D, Alt FW, Acharya P, Haynes BF. Wiehe K, et al. Among authors: tam yk. Cell Host Microbe. 2024 May 8;32(5):693-709.e7. doi: 10.1016/j.chom.2024.04.006. Epub 2024 Apr 25. Cell Host Microbe. 2024. PMID: 38670093
206 results