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Epigenome-wide impact of MAT2A sustains the androgen-indifferent state and confers synthetic vulnerability in ERG fusion-positive prostate cancer.
Cacciatore A, Shinde D, Musumeci C, Sandrini G, Guarrera L, Albino D, Civenni G, Storelli E, Mosole S, Federici E, Fusina A, Iozzo M, Rinaldi A, Pecoraro M, Geiger R, Bolis M, Catapano CV, Carbone GM. Cacciatore A, et al. Among authors: civenni g. Nat Commun. 2024 Aug 6;15(1):6672. doi: 10.1038/s41467-024-50908-7. Nat Commun. 2024. PMID: 39107274 Free PMC article.
EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer.
Zoma M, Curti L, Shinde D, Albino D, Mitra A, Sgrignani J, Mapelli SN, Sandrini G, Civenni G, Merulla J, Chiorino G, Kunderfranco P, Cacciatore A, Kokanovic A, Rinaldi A, Cavalli A, Catapano CV, Carbone GM. Zoma M, et al. Among authors: civenni g. Nat Commun. 2021 Jul 6;12(1):4147. doi: 10.1038/s41467-021-24380-6. Nat Commun. 2021. PMID: 34230470 Free PMC article.
A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.
Pisignano G, Napoli S, Magistri M, Mapelli SN, Pastori C, Di Marco S, Civenni G, Albino D, Enriquez C, Allegrini S, Mitra A, D'Ambrosio G, Mello-Grand M, Chiorino G, Garcia-Escudero R, Varani G, Carbone GM, Catapano CV. Pisignano G, et al. Among authors: civenni g. Nat Commun. 2017 May 30;8:15622. doi: 10.1038/ncomms15622. Nat Commun. 2017. PMID: 28555645 Free PMC article.
Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer.
Civenni G, Bosotti R, Timpanaro A, Vàzquez R, Merulla J, Pandit S, Rossi S, Albino D, Allegrini S, Mitra A, Mapelli SN, Vierling L, Giurdanella M, Marchetti M, Paganoni A, Rinaldi A, Losa M, Mira-Catò E, D'Antuono R, Morone D, Rezai K, D'Ambrosio G, Ouafik L, Mackenzie S, Riveiro ME, Cvitkovic E, Carbone GM, Catapano CV. Civenni G, et al. Cell Metab. 2019 Aug 6;30(2):303-318.e6. doi: 10.1016/j.cmet.2019.05.004. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130467 Free article.
53 results