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CC chemokine receptor 2 is allosterically modulated by sodium ions and amiloride derivatives through a distinct sodium ion binding site.
den Hollander LS, Zweemer AJM, Béquignon OJM, Hammerl DM, Bleijs BTM, Veenhuizen M, Lantsheer WJF, Chau B, van Westen GJP, IJzerman AP, Heitman LH. den Hollander LS, et al. Among authors: bleijs btm. Biochem Pharmacol. 2024 Nov;229:116464. doi: 10.1016/j.bcp.2024.116464. Epub 2024 Aug 5. Biochem Pharmacol. 2024. PMID: 39111604