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Human organoids with an autologous tissue-resident immune compartment.
Recaldin T, Steinacher L, Gjeta B, Harter MF, Adam L, Kromer K, Mendes MP, Bellavista M, Nikolaev M, Lazzaroni G, Krese R, Kilik U, Popovic D, Stoll B, Gerard R, Bscheider M, Bickle M, Cabon L, Camp JG, Gjorevski N. Recaldin T, et al. Among authors: bscheider m. Nature. 2024 Sep;633(8028):165-173. doi: 10.1038/s41586-024-07791-5. Epub 2024 Aug 14. Nature. 2024. PMID: 39143209 Free PMC article.
Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids.
Harter MF, Recaldin T, Gerard R, Avignon B, Bollen Y, Esposito C, Guja-Jarosz K, Kromer K, Filip A, Aubert J, Schneider A, Bacac M, Bscheider M, Stokar-Regenscheit N, Piscuoglio S, Beumer J, Gjorevski N. Harter MF, et al. Among authors: bscheider m. Nat Biomed Eng. 2024 Apr;8(4):345-360. doi: 10.1038/s41551-023-01156-5. Epub 2023 Dec 19. Nat Biomed Eng. 2024. PMID: 38114742 Free PMC article.
Profiling the heterogeneity of colorectal cancer consensus molecular subtypes using spatial transcriptomics.
Valdeolivas A, Amberg B, Giroud N, Richardson M, Gálvez EJC, Badillo S, Julien-Laferrière A, Túrós D, Voith von Voithenberg L, Wells I, Pesti B, Lo AA, Yángüez E, Das Thakur M, Bscheider M, Sultan M, Kumpesa N, Jacobsen B, Bergauer T, Saez-Rodriguez J, Rottenberg S, Schwalie PC, Hahn K. Valdeolivas A, et al. Among authors: bscheider m. NPJ Precis Oncol. 2024 Jan 10;8(1):10. doi: 10.1038/s41698-023-00488-4. NPJ Precis Oncol. 2024. PMID: 38200223 Free PMC article.
Modeling memory B cell responses in a lymphoid organ-chip to evaluate mRNA vaccine boosting.
Jeger-Madiot R, Planas D, Staropoli I, Debarnot H, Kervevan J, Mary H, Collina C, Fonseca BF, Robinot R, Gellenoncourt S, Schwartz O, Ewart L, Bscheider M, Gobaa S, Chakrabarti LA. Jeger-Madiot R, et al. Among authors: bscheider m. J Exp Med. 2024 Oct 7;221(10):e20240289. doi: 10.1084/jem.20240289. Epub 2024 Sep 6. J Exp Med. 2024. PMID: 39240335 Free article.
Age-Specific ADME Gene Expression in Infant Intestinal Enteroids.
Streekstra EJ, Scheer-Weijers T, Bscheider M, Fuerst-Recktenwald S, Roth A, van Ijzendoorn SCD, Botden S, de Boode W, Stommel MWJ, Greupink R, Russel FGM, van de Steeg E, de Wildt SN. Streekstra EJ, et al. Among authors: bscheider m. Mol Pharm. 2024 Sep 2;21(9):4347-4355. doi: 10.1021/acs.molpharmaceut.4c00302. Epub 2024 Aug 9. Mol Pharm. 2024. PMID: 39120063 Free PMC article.
Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies.
Kerns SJ, Belgur C, Petropolis D, Kanellias M, Barrile R, Sam J, Weinzierl T, Fauti T, Freimoser-Grundschober A, Eckmann J, Hage C, Geiger M, Ng PR, Tien-Street W, Manatakis DV, Micallef V, Gerard R, Bscheider M, Breous-Nystrom E, Schneider A, Giusti AM, Bertinetti-Lapatki C, Grant HS, Roth AB, Hamilton GA, Singer T, Karalis K, Moisan A, Bruenker P, Klein C, Bacac M, Gjorevski N, Cabon L. Kerns SJ, et al. Among authors: bscheider m. Elife. 2021 Aug 11;10:e67106. doi: 10.7554/eLife.67106. Elife. 2021. PMID: 34378534 Free PMC article.
23 results