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Novel GPIb-independent platelet aggregation induced by botrocetin: implications for diagnosis and antithrombotic therapy.
Shen C, Mackeigan DT, Shoara AA, Bhoria P, Zhu G, Karakas D, Ma W, Chen ZY, Xu R, Slavkovic S, Zhang D, Prifti V, Liu Z, Cerenzia EG, Chen P, Neves MAD, Li H, Xue F, Yang R, Liu J, Lai R, Li R, Ni H. Shen C, et al. Among authors: chen zy, chen p. J Thromb Haemost. 2024 Nov;22(11):3249-3265. doi: 10.1016/j.jtha.2024.06.030. Epub 2024 Aug 13. J Thromb Haemost. 2024. PMID: 39147240
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα.
Shen C, Mackeigan DT, Shoara AA, Xu R, Bhoria P, Karakas D, Ma W, Cerenzia E, Chen Z, Hoard B, Lin L, Lei X, Zhu G, Chen P, Johnson PE, Ni H. Shen C, et al. Among authors: chen z, chen p. J Thromb Haemost. 2023 May;21(5):1274-1288. doi: 10.1016/j.jtha.2022.12.030. Epub 2023 Jan 9. J Thromb Haemost. 2023. PMID: 36732162 Free article.
The 14-3-3ζ-c-Src-integrin-β3 complex is vital for platelet activation.
Shen C, Liu M, Xu R, Wang G, Li J, Chen P, Ma W, Mwangi J, Lu Q, Duan Z, Zhang Z, Dahmani FZ, Mackeigan DT, Ni H, Lai R. Shen C, et al. Among authors: chen p. Blood. 2020 Aug 20;136(8):974-988. doi: 10.1182/blood.2019002314. Blood. 2020. PMID: 32584951 Free article.
SARS-CoV-2 RBD and Its Variants Can Induce Platelet Activation and Clearance: Implications for Antibody Therapy and Vaccinations against COVID-19.
Ma X, Liang J, Zhu G, Bhoria P, Shoara AA, MacKeigan DT, Khoury CJ, Slavkovic S, Lin L, Karakas D, Chen Z, Prifti V, Liu Z, Shen C, Li Y, Zhang C, Dou J, Rousseau Z, Zhang J, Ni T, Lei X, Chen P, Wu X, Shaykhalishahi H, Mubareka S, Connelly KA, Zhang H, Rotstein O, Ni H. Ma X, et al. Among authors: chen z, chen p. Research (Wash D C). 2023 Apr 24;6:0124. doi: 10.34133/research.0124. eCollection 2023. Research (Wash D C). 2023. PMID: 37223472 Free PMC article.
The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.
Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H. Li C, et al. Among authors: chen p. J Clin Invest. 2011 Nov;121(11):4537-47. doi: 10.1172/JCI57850. Epub 2011 Oct 24. J Clin Invest. 2011. PMID: 22019589 Free PMC article.
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