Xiao Q - Search Results

1

Engineered IscB-ωRNA system with expanded target range for base editing.

Xiao Q, Li G, Han D, Wang H, Yao M, Ma T, Zhou J, Zhang Y, Zhang X, He B, Yuan Y, Shi L, Li T, Yang H, Huang J, Zhang H. Xiao Q, et al. Nat Chem Biol. 2025 Jan;21(1):100-108. doi: 10.1038/s41589-024-01706-1. Epub 2024 Aug 15. Nat Chem Biol. 2025. PMID: 39147927 Free PMC article.

2

Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors.

Zhang M, Zhou C, Wei Y, Xu C, Pan H, Ying W, Sun Y, Sun Y, Xiao Q, Yao N, Zhong W, Li Y, Wu K, Yuan G, Mitalipov S, Chen ZJ, Yang H. Zhang M, et al. Among authors: xiao q. Genome Biol. 2019 May 22;20(1):101. doi: 10.1186/s13059-019-1703-6. Genome Biol. 2019. PMID: 31118069 Free PMC article.

3

Screened AAV variants permit efficient transduction access to supporting cells and hair cells.

Hu X, Wang J, Yao X, Xiao Q, Xue Y, Wang S, Shi L, Shu Y, Li H, Yang H. Hu X, et al. Among authors: xiao q. Cell Discov. 2019 Oct 15;5:49. doi: 10.1038/s41421-019-0115-9. eCollection 2019. Cell Discov. 2019. PMID: 31636961 Free PMC article. No abstract available.

4

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice.

Zhou H, Su J, Hu X, Zhou C, Li H, Chen Z, Xiao Q, Wang B, Wu W, Sun Y, Zhou Y, Tang C, Liu F, Wang L, Feng C, Liu M, Li S, Zhang Y, Xu H, Yao H, Shi L, Yang H. Zhou H, et al. Among authors: xiao q. Cell. 2020 Apr 30;181(3):590-603.e16. doi: 10.1016/j.cell.2020.03.024. Epub 2020 Apr 8. Cell. 2020. PMID: 32272060 Free article.

5

Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs.

Gao N, Hu J, He B, Ji Z, Hu X, Huang J, Wei Y, Peng J, Wei Y, Zhou Y, Shen X, Li H, Feng X, Xiao Q, Shi L, Sun Y, Zhou C, Zhou H, Yang H. Gao N, et al. Among authors: xiao q. Nat Cell Biol. 2021 Jan;23(1):99-108. doi: 10.1038/s41556-020-00610-9. Epub 2021 Jan 4. Nat Cell Biol. 2021. PMID: 33398178

6

Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes.

Xu C, Zhou Y, Xiao Q, He B, Geng G, Wang Z, Cao B, Dong X, Bai W, Wang Y, Wang X, Zhou D, Yuan T, Huo X, Lai J, Yang H. Xu C, et al. Among authors: xiao q. Nat Methods. 2021 May;18(5):499-506. doi: 10.1038/s41592-021-01124-4. Epub 2021 May 3. Nat Methods. 2021. PMID: 33941935

7

Author Correction: Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes.

Xu C, Zhou Y, Xiao Q, He B, Geng G, Wang Z, Cao B, Dong X, Bai W, Wang Y, Wang X, Zhou D, Yuan T, Huo X, Lai J, Yang H. Xu C, et al. Among authors: xiao q. Nat Methods. 2022 Feb;19(2):255. doi: 10.1038/s41592-021-01379-x. Nat Methods. 2022. PMID: 34975157 No abstract available.

8

Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor.

Xiao Q, Xu Z, Xue Y, Xu C, Han L, Liu Y, Wang F, Zhang R, Han S, Wang X, Li GL, Li H, Yang H, Shu Y. Xiao Q, et al. Sci Transl Med. 2022 Jul 20;14(654):eabn0449. doi: 10.1126/scitranslmed.abn0449. Epub 2022 Jul 20. Sci Transl Med. 2022. PMID: 35857824

9

High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects.

Tong H, Huang J, Xiao Q, He B, Dong X, Liu Y, Yang X, Han D, Wang Z, Wang X, Ying W, Zhang R, Wei Y, Xu C, Zhou Y, Li Y, Cai M, Wang Q, Xue M, Li G, Fang K, Zhang H, Yang H. Tong H, et al. Among authors: xiao q. Nat Biotechnol. 2023 Jan;41(1):108-119. doi: 10.1038/s41587-022-01419-7. Epub 2022 Aug 11. Nat Biotechnol. 2023. PMID: 35953673

10

Mini-dCas13X-mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy.

Li G, Jin M, Li Z, Xiao Q, Lin J, Yang D, Liu Y, Wang X, Xie L, Ying W, Wang H, Zuo E, Shi L, Wang N, Chen W, Xu C, Yang H. Li G, et al. Among authors: xiao q. J Clin Invest. 2023 Feb 1;133(3):e162809. doi: 10.1172/JCI162809. J Clin Invest. 2023. PMID: 36512423 Free PMC article.

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