Stewart GR - Search Results

1

Identification of gene targets that potentiate the action of rifampicin on Mycobacterium bovis BCG.

Chand P, Mendum TA, Butler RE, Hingley-Wilson SM, Stewart GR. Chand P, et al. Among authors: stewart gr. Microbiology (Reading). 2024 Aug;170(8):001488. doi: 10.1099/mic.0.001488. Microbiology (Reading). 2024. PMID: 39150447 Free PMC article.

2

Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle.

Mendum TA, Chandran A, Williams K, Vordermeier HM, Villarreal-Ramos B, Wu H, Singh A, Smith AA, Butler RE, Prasad A, Bharti N, Banerjee R, Kasibhatla SM, Bhatt A, Stewart GR, McFadden J. Mendum TA, et al. Among authors: stewart gr. BMC Genomics. 2019 May 28;20(1):431. doi: 10.1186/s12864-019-5791-1. BMC Genomics. 2019. PMID: 31138110 Free PMC article.

3

Effective generation of reactive oxygen species in the mycobacterial phagosome requires K+ efflux from the bacterium.

Butler RE, Cihlarova V, Stewart GR. Butler RE, et al. Among authors: stewart gr. Cell Microbiol. 2010 Aug;12(8):1186-93. doi: 10.1111/j.1462-5822.2010.01463.x. Epub 2010 Mar 19. Cell Microbiol. 2010. PMID: 20331644

4

ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage.

Estorninho M, Smith H, Thole J, Harders-Westerveen J, Kierzek A, Butler RE, Neyrolles O, Stewart GR. Estorninho M, et al. Among authors: stewart gr. Microbiology (Reading). 2010 Nov;156(Pt 11):3445-3455. doi: 10.1099/mic.0.042275-0. Epub 2010 Aug 5. Microbiology (Reading). 2010. PMID: 20688819 Free article.

5

Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells.

Mendum TA, Wu H, Kierzek AM, Stewart GR. Mendum TA, et al. Among authors: stewart gr. BMC Genomics. 2015 May 9;16(1):372. doi: 10.1186/s12864-015-1569-2. BMC Genomics. 2015. PMID: 25956932 Free PMC article.

6

Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum.

Butler RE, Smith AA, Mendum TA, Chandran A, Wu H, Lefrançois L, Chambers M, Soldati T, Stewart GR. Butler RE, et al. Among authors: stewart gr. ISME J. 2020 Apr;14(4):919-930. doi: 10.1038/s41396-019-0572-z. Epub 2020 Jan 2. ISME J. 2020. PMID: 31896783 Free PMC article.

7

Genetic screening for the protective antigenic targets of BCG vaccination.

Smith AA, Villarreal-Ramos B, Mendum TA, Williams KJ, Jones GJ, Wu H, McFadden J, Vordermeier HM, Stewart GR. Smith AA, et al. Among authors: stewart gr. Tuberculosis (Edinb). 2020 Sep;124:101979. doi: 10.1016/j.tube.2020.101979. Epub 2020 Aug 1. Tuberculosis (Edinb). 2020. PMID: 32814303

8

Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals the genetic requirement for virulence and survival in amoebae and microglial cells.

Lefrançois LH, Nitschke J, Wu H, Panis G, Prados J, Butler RE, Mendum TA, Hanna N, Stewart GR, Soldati T. Lefrançois LH, et al. Among authors: stewart gr. mSystems. 2024 Feb 20;9(2):e0132623. doi: 10.1128/msystems.01326-23. Epub 2024 Jan 25. mSystems. 2024. PMID: 38270456 Free PMC article.

9

Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca2+ influx, necrosis and neutrophil extracellular trap formation.

Francis RJ, Butler RE, Stewart GR. Francis RJ, et al. Among authors: stewart gr. Cell Death Dis. 2014 Oct 16;5(10):e1474. doi: 10.1038/cddis.2014.394. Cell Death Dis. 2014. PMID: 25321481 Free PMC article.

10

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.

Butler RE, Brodin P, Jang J, Jang MS, Robertson BD, Gicquel B, Stewart GR. Butler RE, et al. Among authors: stewart gr. PLoS One. 2012;7(10):e47573. doi: 10.1371/journal.pone.0047573. Epub 2012 Oct 30. PLoS One. 2012. PMID: 23118880 Free PMC article.

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