Wiegant WW - Search Results

1

The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks.

van de Kooij B, van der Wal FJ, Rother MB, Wiegant WW, Creixell P, Stout M, Joughin BA, Vornberger J, Altmeyer M, van Vugt MATM, Yaffe MB, van Attikum H. van de Kooij B, et al. Among authors: wiegant ww. Nat Commun. 2024 Aug 16;15(1):7076. doi: 10.1038/s41467-024-51090-6. Nat Commun. 2024. PMID: 39152113 Free PMC article.

2

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

Rother MB, Pellegrino S, Smith R, Gatti M, Meisenberg C, Wiegant WW, Luijsterburg MS, Imhof R, Downs JA, Vertegaal ACO, Huet S, Altmeyer M, van Attikum H. Rother MB, et al. Among authors: wiegant ww. Nat Commun. 2020 Nov 13;11(1):5775. doi: 10.1038/s41467-020-19502-5. Nat Commun. 2020. PMID: 33188175 Free PMC article.

3

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining.

Singh JK, Smith R, Rother MB, de Groot AJL, Wiegant WW, Vreeken K, D'Augustin O, Kim RQ, Qian H, Krawczyk PM, González-Prieto R, Vertegaal ACO, Lamers M, Huet S, van Attikum H. Singh JK, et al. Among authors: wiegant ww. Nat Commun. 2021 Nov 12;12(1):6560. doi: 10.1038/s41467-021-26691-0. Nat Commun. 2021. PMID: 34772923 Free PMC article.

4

The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks.

van de Kooij B, van der Wal FJ, Rother MB, Creixell P, Stout M, Wiegant W, Joughin BA, Vornberger J, van Vugt MATM, Altmeyer M, Yaffe MB, van Attikum H. van de Kooij B, et al. bioRxiv [Preprint]. 2023 Sep 6:2023.09.05.556391. doi: 10.1101/2023.09.05.556391. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 16;15(1):7076. doi: 10.1038/s41467-024-51090-6 PMID: 37732274 Free PMC article. Updated. Preprint.

5

Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining.

Helfricht A, Wiegant WW, Thijssen PE, Vertegaal AC, Luijsterburg MS, van Attikum H. Helfricht A, et al. Among authors: wiegant ww. Cell Cycle. 2013 Sep 15;12(18):3070-82. doi: 10.4161/cc.26033. Epub 2013 Aug 20. Cell Cycle. 2013. PMID: 23974106 Free PMC article.

6

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.

Velimezi G, Robinson-Garcia L, Muñoz-Martínez F, Wiegant WW, Ferreira da Silva J, Owusu M, Moder M, Wiedner M, Rosenthal SB, Fisch KM, Moffat J, Menche J, van Attikum H, Jackson SP, Loizou JI. Velimezi G, et al. Among authors: wiegant ww. Nat Commun. 2018 Jun 11;9(1):2280. doi: 10.1038/s41467-018-04649-z. Nat Commun. 2018. PMID: 29891926 Free PMC article.

7

Functional analysis of genetic variants in the high-risk breast cancer susceptibility gene PALB2.

Boonen RACM, Rodrigue A, Stoepker C, Wiegant WW, Vroling B, Sharma M, Rother MB, Celosse N, Vreeswijk MPG, Couch F, Simard J, Devilee P, Masson JY, van Attikum H. Boonen RACM, et al. Among authors: wiegant ww. Nat Commun. 2019 Nov 22;10(1):5296. doi: 10.1038/s41467-019-13194-2. Nat Commun. 2019. PMID: 31757951 Free PMC article.

8

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks.

Alonso-de Vega I, Paz-Cabrera MC, Rother MB, Wiegant WW, Checa-Rodríguez C, Hernández-Fernaud JR, Huertas P, Freire R, van Attikum H, Smits VAJ. Alonso-de Vega I, et al. Among authors: wiegant ww. Nucleic Acids Res. 2020 May 21;48(9):4915-4927. doi: 10.1093/nar/gkaa196. Nucleic Acids Res. 2020. PMID: 32232336 Free PMC article.

9

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.

Costelloe T, Louge R, Tomimatsu N, Mukherjee B, Martini E, Khadaroo B, Dubois K, Wiegant WW, Thierry A, Burma S, van Attikum H, Llorente B. Costelloe T, et al. Among authors: wiegant ww. Nature. 2012 Sep 27;489(7417):581-4. doi: 10.1038/nature11353. Epub 2012 Sep 9. Nature. 2012. PMID: 22960744 Free PMC article.

10

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

Typas D, Luijsterburg MS, Wiegant WW, Diakatou M, Helfricht A, Thijssen PE, van den Broek B, Mullenders LH, van Attikum H. Typas D, et al. Among authors: wiegant ww. Nucleic Acids Res. 2015 Aug 18;43(14):6919-33. doi: 10.1093/nar/gkv613. Epub 2015 Jun 22. Nucleic Acids Res. 2015. PMID: 26101254 Free PMC article.

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