Keov P - Search Results

1

Biased receptor signalling and intracellular trafficking profiles of structurally distinct formylpeptide receptor 2 agonists.

Peng C, Vecchio EA, Nguyen ATN, De Seram M, Tang R, Keov P, Woodman OL, Chen YC, Baell J, May LT, Zhao P, Ritchie RH, Qin CX. Peng C, et al. Among authors: keov p. Br J Pharmacol. 2024 Nov;181(22):4677-4692. doi: 10.1111/bph.17310. Epub 2024 Aug 18. Br J Pharmacol. 2024. PMID: 39154373

2

Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor.

Tomašević N, Emser FS, Muratspahić E, Gattringer J, Hasinger S, Hellinger R, Keov P, Felkl M, Gertsch J, Becker CFW, Gruber CW. Tomašević N, et al. Among authors: keov p. J Biol Chem. 2024 Jun;300(6):107330. doi: 10.1016/j.jbc.2024.107330. Epub 2024 Apr 26. J Biol Chem. 2024. PMID: 38679329 Free PMC article.

3

Development of a Novel Assay for Direct Assessment of Selective Amylin Receptor Activation Reveals Novel Differences in Behavior of Selective and Nonselective Peptide Agonists.

Keov P, Christopoulos G, Hick CA, Glendorf T, Ballarín-González B, Wootten D, Sexton PM. Keov P, et al. Mol Pharmacol. 2024 Apr 17;105(5):359-373. doi: 10.1124/molpharm.123.000865. Mol Pharmacol. 2024. PMID: 38458773

4

Role of G protein-coupled receptor kinases (GRKs) in β₂ -adrenoceptor-mediated glucose uptake.

Ham S, Mukaida S, Sato M, Keov P, Bengtsson T, Furness S, Holliday ND, Evans BA, Summers RJ, Hutchinson DS. Ham S, et al. Among authors: keov p. Pharmacol Res Perspect. 2024 Feb;12(1):e1176. doi: 10.1002/prp2.1176. Pharmacol Res Perspect. 2024. PMID: 38332691 Free PMC article.

5

Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin.

Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Dürrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, Gruber CW, Muttenthaler M. Dekan Z, et al. Among authors: keov p. Chem Sci. 2021 Feb 4;12(11):4057-4062. doi: 10.1039/d0sc05501h. Chem Sci. 2021. PMID: 34163676 Free PMC article.

6

AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists.

Fletcher MM, Keov P, Truong TT, Mennen G, Hick CA, Zhao P, Furness SGB, Kruse T, Clausen TR, Wootten D, Sexton PM. Fletcher MM, et al. Among authors: keov p. J Pharmacol Exp Ther. 2021 Jun;377(3):417-440. doi: 10.1124/jpet.121.000567. Epub 2021 Mar 16. J Pharmacol Exp Ther. 2021. PMID: 33727283

7

Orphan receptor GPR37L1 remains unliganded.

Ngo T, Wilkins BP, So SS, Keov P, Chahal KK, Finch AM, Coleman JLJ, Kufareva I, Smith NJ. Ngo T, et al. Among authors: keov p. Nat Chem Biol. 2021 Apr;17(4):383-386. doi: 10.1038/s41589-021-00748-z. Epub 2021 Mar 1. Nat Chem Biol. 2021. PMID: 33649602 Free PMC article. No abstract available.

8

I8-arachnotocin-an arthropod-derived G protein-biased ligand of the human vasopressin V₂ receptor.

Duerrauer L, Muratspahić E, Gattringer J, Keov P, Mendel HC, Pfleger KDG, Muttenthaler M, Gruber CW. Duerrauer L, et al. Among authors: keov p. Sci Rep. 2019 Dec 17;9(1):19295. doi: 10.1038/s41598-019-55675-w. Sci Rep. 2019. PMID: 31848378 Free PMC article.

9

The TRPV4 Agonist GSK1016790A Regulates the Membrane Expression of TRPV4 Channels.

Baratchi S, Keov P, Darby WG, Lai A, Khoshmanesh K, Thurgood P, Vahidi P, Ejendal K, McIntyre P. Baratchi S, et al. Among authors: keov p. Front Pharmacol. 2019 Jan 23;10:6. doi: 10.3389/fphar.2019.00006. eCollection 2019. Front Pharmacol. 2019. PMID: 30728775 Free PMC article.

10

Discovery of peptide probes to modulate oxytocin-type receptors of insects.

Keov P, Liutkevičiūtė Z, Hellinger R, Clark RJ, Gruber CW. Keov P, et al. Sci Rep. 2018 Jul 3;8(1):10020. doi: 10.1038/s41598-018-28380-3. Sci Rep. 2018. PMID: 29968789 Free PMC article.

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