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Synthetic Process Development of (R)-(+)-1,2-Epoxy-5-hexene: An Important Chiral Building Block.
Guthrie D, Saathoff JM, Sahani RL, Nunes De Souza A, Cook DW, Hochstetler SR, Burns JM, Moazeni-Pourasil RS, Wierzbicki J, Ahmad S, Laidlaw GM, Gupton BF, Shanahan CS, Klumpp DA, Jin L. Guthrie D, et al. Among authors: gupton bf. Org Process Res Dev. 2024 Aug 1;28(8):3197-3205. doi: 10.1021/acs.oprd.4c00101. eCollection 2024 Aug 16. Org Process Res Dev. 2024. PMID: 39171130 Free PMC article.
High throughput photo-oxidations in a packed bed reactor system.
Kong CJ, Fisher D, Desai BK, Yang Y, Ahmad S, Belecki K, Gupton BF. Kong CJ, et al. Among authors: gupton bf. Bioorg Med Chem. 2017 Dec 1;25(23):6203-6208. doi: 10.1016/j.bmc.2017.07.004. Epub 2017 Jul 6. Bioorg Med Chem. 2017. PMID: 29054711
High-yielding continuous-flow synthesis of antimalarial drug hydroxychloroquine.
Yu E, Mangunuru HPR, Telang NS, Kong CJ, Verghese J, Gilliland Iii SE, Ahmad S, Dominey RN, Gupton BF. Yu E, et al. Among authors: gupton bf. Beilstein J Org Chem. 2018 Mar 8;14:583-592. doi: 10.3762/bjoc.14.45. eCollection 2018. Beilstein J Org Chem. 2018. PMID: 29623120 Free PMC article.
Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis.
Gopalsamuthiram V, Kadam AL, Noble JK, Snead DR, Williams C, Jamison TF, Senanayake C, Yadaw AK, Roy S, Sirasani G, Gupton BF, Burns J, Cook DW, Stringham RW, Ahmad S, Krack R. Gopalsamuthiram V, et al. Among authors: gupton bf. Org Process Res Dev. 2021 Dec 17;25(12):2679-2685. doi: 10.1021/acs.oprd.1c00219. Epub 2021 Dec 9. Org Process Res Dev. 2021. PMID: 34955627 Free PMC article. Review.
36 results