Klumpp DA - Search Results

1

Synthetic Process Development of (R)-(+)-1,2-Epoxy-5-hexene: An Important Chiral Building Block.

Guthrie D, Saathoff JM, Sahani RL, Nunes De Souza A, Cook DW, Hochstetler SR, Burns JM, Moazeni-Pourasil RS, Wierzbicki J, Ahmad S, Laidlaw GM, Gupton BF, Shanahan CS, Klumpp DA, Jin L. Guthrie D, et al. Among authors: klumpp da. Org Process Res Dev. 2024 Aug 1;28(8):3197-3205. doi: 10.1021/acs.oprd.4c00101. eCollection 2024 Aug 16. Org Process Res Dev. 2024. PMID: 39171130 Free PMC article.

2

Practical Synthesis of 7-Bromo-4-chloro-1H-indazol-3-amine: An Important Intermediate to Lenacapavir.

Asad N, Lyons M, Muniz Machado Rodrigues S, Burns JM, Roper TD, Laidlaw GM, Ahmad S, Gupton BF, Klumpp D, Jin L. Asad N, et al. Molecules. 2024 Jun 7;29(12):2705. doi: 10.3390/molecules29122705. Molecules. 2024. PMID: 38930779 Free PMC article.

3

A New Synthesis of Enantiopure Amine Fragment: An Important Intermediate to the Anti-HIV Drug Lenacapavir.

Shinde AH, Sayini R, Singh P, Burns JM, Ahmad S, Laidlaw GM, Gupton BF, Klumpp DA, Jin L. Shinde AH, et al. Among authors: klumpp da. J Org Chem. 2025 Jan 10;90(1):471-478. doi: 10.1021/acs.joc.4c02380. Epub 2024 Dec 16. J Org Chem. 2025. PMID: 39680644 Free PMC article.

4

Superelectrophilic Nonclassical Carbocations.

Hood JC, Esteves P, Gembicky M, Klumpp DA. Hood JC, et al. Among authors: klumpp da. J Org Chem. 2024 Jul 19;89(14):9744-9749. doi: 10.1021/acs.joc.3c02870. Epub 2024 Jul 2. J Org Chem. 2024. PMID: 38955424

5

Friedel-Crafts Reactions with N-Heterocyclic Alcohols.

Hood JC, Anokhin MV, Klumpp DA. Hood JC, et al. Among authors: klumpp da. J Org Chem. 2023 Aug 4;88(15):10483-10493. doi: 10.1021/acs.joc.3c00403. Epub 2023 Jul 20. J Org Chem. 2023. PMID: 37471592

6

Synthesis of warfarin analogs: conjugate addition reactions of alkenyl-substituted N-heterocycles with 4-hydroxycoumarin and related substrates.

Goka B, Klumpp DA. Goka B, et al. Among authors: klumpp da. RSC Adv. 2023 Feb 6;13(7):4754-4756. doi: 10.1039/d3ra00251a. eCollection 2023 Jan 31. RSC Adv. 2023. PMID: 36760300 Free PMC article.

7

Superacid Promoted Synthesis of 9,9'-Spirobifluorenes and Related Aza- and Diazaspirocycles.

Hood JC, Klumpp DA. Hood JC, et al. Among authors: klumpp da. J Org Chem. 2023 Jan 6;88(1):665-669. doi: 10.1021/acs.joc.2c01880. Epub 2022 Dec 19. J Org Chem. 2023. PMID: 36535021

8

Double Addition Reactions Involving Vinyl-Substituted N-Heterocycles and Active Methylene Compounds.

Hood JC, Tshikaya Y, Manz AR, LaPorte MC, Klumpp DA. Hood JC, et al. Among authors: klumpp da. J Org Chem. 2022 Apr 1;87(7):4908-4911. doi: 10.1021/acs.joc.1c02655. Epub 2022 Mar 10. J Org Chem. 2022. PMID: 35271287

9

Superacid-promoted synthesis of quinoline derivatives.

Vuong H, Stentzel MR, Klumpp DA. Vuong H, et al. Among authors: klumpp da. Tetrahedron Lett. 2020 Mar 19;61(12):151630. doi: 10.1016/j.tetlet.2020.151630. Epub 2020 Jan 14. Tetrahedron Lett. 2020. PMID: 33299258 Free PMC article.

10

Michael Addition with an Olefinic Pyridine: Organometallic Nucleophiles and Carbon Electrophiles.

Stentzel MR, Klumpp DA. Stentzel MR, et al. Among authors: klumpp da. J Org Chem. 2020 Oct 2;85(19):12740-12746. doi: 10.1021/acs.joc.0c00823. Epub 2020 Sep 15. J Org Chem. 2020. PMID: 32883082 Free PMC article.

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