Shizu R - Search Results

1

Comparative study on gene expression profiles in the liver of male neonatal mice prenatally exposed to PFOA and its alternative HFPO-DA.

Murase W, Kubota A, Hakota R, Yasuda A, Ikeda A, Nakagawa K, Shizu R, Yoshinari K, Kojima H. Murase W, et al. Among authors: shizu r. Toxicology. 2025 Jan 6;511:154048. doi: 10.1016/j.tox.2025.154048. Online ahead of print. Toxicology. 2025. PMID: 39778857

2

Diacylglycerol kinase ζ is a positive insulin secretion regulator in pancreatic β-cell line MIN6.

Watanabe N, Kaneko YK, Ishihara H, Shizu R, Yoshinari K, Yamaguchi M, Kimura T, Ishikawa T. Watanabe N, et al. Among authors: shizu r. Biochem Biophys Res Commun. 2025 Jan;742:151109. doi: 10.1016/j.bbrc.2024.151109. Epub 2024 Dec 2. Biochem Biophys Res Commun. 2025. PMID: 39644605

3

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression.

Sato T, Shizu R, Baba R, Ooka A, Hosaka T, Kanno Y, Yoshinari K. Sato T, et al. Among authors: shizu r. Biochem J. 2024 Sep 18;481(18):1173-1186. doi: 10.1042/BCJ20240172. Biochem J. 2024. PMID: 39171361

4

Utility of human cytochrome P450 inhibition data in the assessment of drug-induced liver injury.

Kaito S, Takeshita JI, Iwata M, Sasaki T, Hosaka T, Shizu R, Yoshinari K. Kaito S, et al. Among authors: shizu r. Xenobiotica. 2024 Jul;54(7):411-419. doi: 10.1080/00498254.2024.2312505. Epub 2024 Aug 21. Xenobiotica. 2024. PMID: 38315106

5

Interaction with YAP underlies the species differences between humans and rodents in CAR-dependent hepatocyte proliferation.

Shizu R, Makida N, Sobe K, Ishimura M, Takeshita A, Hosaka T, Kanno Y, Sasaki T, Yoshinari K. Shizu R, et al. Toxicol Sci. 2024 Feb 28;198(1):101-112. doi: 10.1093/toxsci/kfad129. Toxicol Sci. 2024. PMID: 38128062

6

[Understanding the Underlying Mechanism of Xenobiotic-Sensing Nuclear Receptor Activation].

Shizu R. Shizu R. Yakugaku Zasshi. 2023;143(9):701-706. doi: 10.1248/yakushi.23-00110. Yakugaku Zasshi. 2023. PMID: 37661435 Free article. Review. Japanese.

7

Phosphorylation of nuclear receptors: Novelty and therapeutic implications.

Shindo S, Kakizaki S, Sakaki T, Kawasaki Y, Sakuma T, Negishi M, Shizu R. Shindo S, et al. Among authors: shizu r. Pharmacol Ther. 2023 Aug;248:108477. doi: 10.1016/j.pharmthera.2023.108477. Epub 2023 Jun 15. Pharmacol Ther. 2023. PMID: 37330113 Review.

8

Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays.

Murase W, Kubota A, Ikeda-Araki A, Terasaki M, Nakagawa K, Shizu R, Yoshinari K, Kojima H. Murase W, et al. Among authors: shizu r. Toxicology. 2023 Aug 1;494:153577. doi: 10.1016/j.tox.2023.153577. Epub 2023 Jun 9. Toxicology. 2023. PMID: 37302725

9

PPARα Induces the Expression of CAR That Works as a Negative Regulator of PPARα Functions in Mouse Livers.

Shizu R, Otsuka Y, Ishii C, Ezaki K, Yoshinari K. Shizu R, et al. Int J Mol Sci. 2023 Feb 16;24(4):3953. doi: 10.3390/ijms24043953. Int J Mol Sci. 2023. PMID: 36835365 Free PMC article.

10

Screening for DAX1/EWS-FLI1 functional inhibitors identified dihydroorotate dehydrogenase as a therapeutic target for Ewing's sarcoma.

Watanabe M, Kosaka H, Sugawara M, Maemoto M, Ono Y, Uemori T, Shizu R, Yoshinari K. Watanabe M, et al. Among authors: shizu r. Cancer Med. 2023 Apr;12(8):9802-9814. doi: 10.1002/cam4.5741. Epub 2023 Feb 24. Cancer Med. 2023. PMID: 36825574 Free PMC article.

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