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NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia.
Perry CE, Halawani SM, Mukherjee S, Ngaba LV, Lieu M, Lee WD, Davis JG, Adzika GK, Bebenek AN, Bazianos DD, Chen B, Mercado-Ayon E, Flatley LP, Suryawanshi AP, Ho I, Rabinowitz JD, Serai SD, Biko DM, Tamaroff J, DeDio A, Wade K, Lin KY, Livingston DJ, McCormack SE, Lynch DR, Baur JA. Perry CE, et al. Among authors: davis jg. JCI Insight. 2024 Jul 18;9(16):e177152. doi: 10.1172/jci.insight.177152. JCI Insight. 2024. PMID: 39171530 Free PMC article.
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.
Frederick DW, Loro E, Liu L, Davila A Jr, Chellappa K, Silverman IM, Quinn WJ 3rd, Gosai SJ, Tichy ED, Davis JG, Mourkioti F, Gregory BD, Dellinger RW, Redpath P, Migaud ME, Nakamaru-Ogiso E, Rabinowitz JD, Khurana TS, Baur JA. Frederick DW, et al. Among authors: davis jg. Cell Metab. 2016 Aug 9;24(2):269-82. doi: 10.1016/j.cmet.2016.07.005. Cell Metab. 2016. PMID: 27508874 Free PMC article.
204 results