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TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer.
Kortleve D, Hammerl D, van Brakel M, Wijers R, Roelofs D, Kroese K, Timmermans MM, Liao CY, Huang S, Trapman-Jansen A, Foekens R, Michaux J, de Beijer MTA, Buschow SI, Demmers JAA, Kok M, Danen EHJ, Bassani-Sternberg M, Martens JWM, Abbott RJM, Debets R. Kortleve D, et al. Among authors: van brakel m. Cancer Discov. 2024 Dec 2;14(12):2450-2470. doi: 10.1158/2159-8290.CD-24-0168. Cancer Discov. 2024. PMID: 39172012 Free PMC article.
Gene Engineering T Cells with T-Cell Receptor for Adoptive Therapy.
Kortleve D, van Brakel M, Wijers R, Debets R, Hammerl D. Kortleve D, et al. Among authors: van brakel m. Methods Mol Biol. 2022;2453:209-229. doi: 10.1007/978-1-0716-2115-8_13. Methods Mol Biol. 2022. PMID: 35622329 Free PMC article.
T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness.
Lamers CH, van Steenbergen-Langeveld S, van Brakel M, Groot-van Ruijven CM, van Elzakker PM, van Krimpen B, Sleijfer S, Debets R. Lamers CH, et al. Among authors: van steenbergen langeveld s, van brakel m, van elzakker pm, van krimpen b. Hum Gene Ther Methods. 2014 Dec;25(6):345-57. doi: 10.1089/hgtb.2014.051. Hum Gene Ther Methods. 2014. PMID: 25423330 Free PMC article.
TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets.
Straetemans T, van Brakel M, van Steenbergen S, Broertjes M, Drexhage J, Hegmans J, Lambrecht BN, Lamers C, van Der Bruggen P, Coulie PG, Debets R. Straetemans T, et al. Among authors: van steenbergen s, van brakel m, van der bruggen p. Clin Dev Immunol. 2012;2012:586314. doi: 10.1155/2012/586314. Epub 2012 Feb 12. Clin Dev Immunol. 2012. PMID: 22400038 Free PMC article.
CD45RA+CCR7- CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab.
Kunert A, Basak EA, Hurkmans DP, Balcioglu HE, Klaver Y, van Brakel M, Oostvogels AAM, Lamers CHJ, Bins S, Koolen SLW, van der Veldt AAM, Sleijfer S, Mathijssen RHJ, Aerts JGJV, Debets R. Kunert A, et al. Among authors: van brakel m, van der veldt aam. J Immunother Cancer. 2019 Jun 8;7(1):149. doi: 10.1186/s40425-019-0608-y. J Immunother Cancer. 2019. PMID: 31176366 Free PMC article.
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