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SARS-CoV-2 Mpro inhibitor identification using a cellular gain-of-signal assay for high-throughput screening.
Delgado R, Vishwakarma J, Moghadasi SA, Otsuka Y, Shumate J, Cuell A, Tansiongco M, Cooley CB, Chen Y, Dabrowska A, Basu R, Anindita PD, Luo D, Dosa PI, Harki DA, Bannister T, Scampavia L, Spicer TP, Harris RS. Delgado R, et al. Among authors: shumate j. SLAS Discov. 2024 Sep;29(6):100181. doi: 10.1016/j.slasd.2024.100181. Epub 2024 Aug 22. SLAS Discov. 2024. PMID: 39173830 Free PMC article.
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
Otsuka Y, Airola MV, Choi YM, Coant N, Snider J, Cariello C, Saied EM, Arenz C, Bannister T, Rahaim R Jr, Hannun YA, Shumate J, Scampavia L, Haley JD, Spicer TP. Otsuka Y, et al. Among authors: shumate j. SLAS Discov. 2021 Jan;26(1):113-121. doi: 10.1177/2472555220945283. Epub 2020 Jul 31. SLAS Discov. 2021. PMID: 32734807 Free PMC article.
Identification of Potential Modulators of the RGS7/Gβ5/R7BP Complex.
Stoveken HM, Fernandez-Vega V, Muntean BS, Patil DN, Shumate J, Bannister TD, Scampavia L, Spicer TP, Martemyanov KA. Stoveken HM, et al. Among authors: shumate j. SLAS Discov. 2021 Oct;26(9):1177-1188. doi: 10.1177/24725552211020679. Epub 2021 Jun 11. SLAS Discov. 2021. PMID: 34112017 Free PMC article.
High throughput screening for compounds to the orphan nuclear receptor NR2F6.
Smith E, Campbell S, Wilson AN, Shumate J, Baillargeon P, Scampavia L, Kamenecka TM, Spicer TP, Solt LA. Smith E, et al. Among authors: shumate j. SLAS Discov. 2022 Jun;27(4):242-248. doi: 10.1016/j.slasd.2022.03.005. Epub 2022 Mar 21. SLAS Discov. 2022. PMID: 35331960 Free PMC article.
High throughput screening for SARS-CoV-2 helicase inhibitors.
Otsuka Y, Kim E, Krueger A, Shumate J, Wang C, Bdiri B, Ullah S, Park H, Scampavia L, Bannister TD, Chung D, Spicer TP. Otsuka Y, et al. Among authors: shumate j. SLAS Discov. 2024 Sep;29(6):100180. doi: 10.1016/j.slasd.2024.100180. Epub 2024 Aug 22. SLAS Discov. 2024. PMID: 39173831 Free article.
50 results