Wang H - Search Results

1

PINX1 loss confers susceptibility to PARP inhibition in pan-cancer cells.

Huang M, Zhu X, Wang C, He L, Li L, Wang H, Fan G, Wang Y. Huang M, et al. Among authors: wang h, wang y, wang c. Cell Death Dis. 2024 Aug 22;15(8):610. doi: 10.1038/s41419-024-07009-6. Cell Death Dis. 2024. PMID: 39174499 Free PMC article.

2

Key elements for designing and performing a CRISPR/Cas9-based genetic screen.

Shang W, Wang F, Fan G, Wang H. Shang W, et al. Among authors: wang h, wang f. J Genet Genomics. 2017 Sep 20;44(9):439-449. doi: 10.1016/j.jgg.2017.09.005. Epub 2017 Sep 22. J Genet Genomics. 2017. PMID: 28967615 Review.

3

Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy.

Li W, Qiu S, Chen J, Jiang S, Chen W, Jiang J, Wang F, Si W, Shu Y, Wei P, Fan G, Tian R, Wu H, Xu C, Wang H. Li W, et al. Among authors: wang h, wang f. Immunity. 2020 Aug 18;53(2):456-470.e6. doi: 10.1016/j.immuni.2020.07.011. Epub 2020 Aug 5. Immunity. 2020. PMID: 32758419 Free article.

4

NAD⁺ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells.

Wang Y, Wang F, Wang L, Qiu S, Yao Y, Yan C, Xiong X, Chen X, Ji Q, Cao J, Gao G, Li D, Zhang L, Guo Z, Wang R, Wang H, Fan G. Wang Y, et al. Among authors: wang h, wang f, wang l, wang r. Cell Rep. 2021 Aug 10;36(6):109516. doi: 10.1016/j.celrep.2021.109516. Cell Rep. 2021. PMID: 34380043 Free article.

5

Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness.

Chen J, Qiu S, Li W, Wang K, Zhang Y, Yang H, Liu B, Li G, Li L, Chen M, Lan J, Niu J, He P, Cheng L, Fan G, Liu X, Song X, Xu C, Wu H, Wang H. Chen J, et al. Among authors: wang h, wang k. Cell Res. 2023 May;33(5):341-354. doi: 10.1038/s41422-023-00789-0. Epub 2023 Mar 8. Cell Res. 2023. PMID: 36882513 Free PMC article.

6

Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness.

Chen S, Wu Y, Gao Y, Wu C, Wang Y, Hou C, Ren M, Zhang S, Zhu Q, Zhang J, Yao Y, Huang M, Qi YB, Liu XS, Horng T, Wang H, Ye D, Zhu Z, Zhao S, Fan G. Chen S, et al. Among authors: wang h, wang y. Cell Rep. 2023 Oct 31;42(10):113246. doi: 10.1016/j.celrep.2023.113246. Epub 2023 Oct 12. Cell Rep. 2023. PMID: 37831605 Free article.

7

THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development.

Zhang J, Jiang Z, Zhang X, Yang Z, Wang J, Chen J, Chen L, Song M, Zhang Y, Huang M, Chen S, Xiong X, Wang Y, Hao P, Horng T, Zhuang M, Zhang L, Zuo E, Bai F, Zheng J, Wang H, Fan G. Zhang J, et al. Among authors: wang h, wang j, wang y. Nat Struct Mol Biol. 2024 Jan;31(1):54-67. doi: 10.1038/s41594-023-01131-3. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177672

8

NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers.

Zhu X, Li Y, Liu H, Wang Y, Sun R, Jiang Z, Hou C, Hou X, Huang S, Zhang H, Wang H, Jiang B, Yang X, Xu B, Fan G. Zhu X, et al. Among authors: wang h, wang y. Cell Chem Biol. 2024 Jun 20;31(6):1203-1218.e17. doi: 10.1016/j.chembiol.2024.05.007. Cell Chem Biol. 2024. PMID: 38906111

9

PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.

Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, Hu Y, Jiang Y, Ma Y, Wang H, Bennett EJ, Fu G, Hui E. Xu X, et al. Among authors: wang h. J Cell Biol. 2020 Jun 1;219(6):e201905085. doi: 10.1083/jcb.201905085. J Cell Biol. 2020. PMID: 32437509 Free PMC article.

10

CAR-Toner: an AI-driven approach for CAR tonic signaling prediction and optimization.

Qiu S, Chen J, Wu T, Li L, Wang G, Wu H, Song X, Liu X, Wang H. Qiu S, et al. Among authors: wang h, wang g. Cell Res. 2024 May;34(5):386-388. doi: 10.1038/s41422-024-00936-1. Epub 2024 Feb 14. Cell Res. 2024. PMID: 38351128 Free PMC article. No abstract available.

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