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CSF Cytokines and Chemokines Involved in Cytotoxic Cell Function and Risk of Acute 14-Day Mortality in Persons with Advanced HIV and Cryptococcal Meningitis.
Okafor EC, Mukaremera L, Hullsiek KH, Engen N, Tugume L, Ssebambulidde K, Musubire A, Nuwagira E, Mpoza E, Williams DA, Muzoora C, Rhein J, Meya DB, Nielsen K, Boulware DR; ASTRO-CM Team. Okafor EC, et al. J Infect Dis. 2024 Aug 28:jiae421. doi: 10.1093/infdis/jiae421. Online ahead of print. J Infect Dis. 2024. PMID: 39207255
Implementation of single high-dose liposomal amphotericin B based induction therapy for treatment of HIV-associated cryptococcal meningitis in Uganda: a comparative prospective cohort study.
Gakuru J, Kagimu E, Dai B, Okurut S, Nsangi L, Bahr NC, Okirwoth M, Namuju OC, Jarvis JN, Lawrence DS, Ahimbisibwe C, Ellis J, Tadeo KK, Boulware DR, Meya DB, Tugume L. Gakuru J, et al. Among authors: okirwoth m. Clin Infect Dis. 2024 Aug 24:ciae413. doi: 10.1093/cid/ciae413. Online ahead of print. Clin Infect Dis. 2024. PMID: 39180324
Integrated management of cryptococcal meningitis and concurrent opportunistic infections to improve outcomes in advanced HIV disease: a randomised strategy trial.
Ellis J, Nsangi L, Bangdiwala A, Hale G, Gakuru J, Kagimu E, Mugabi T, Kigozi E, Tukundane A, Okirwoth M, Kandole TK, Cresswel F, Harrison TS, Moore D, Fielding K, Meya D, Boulware D, Jarvis JN. Ellis J, et al. Among authors: okirwoth m. Wellcome Open Res. 2024 Jun 5;9:14. doi: 10.12688/wellcomeopenres.19324.2. eCollection 2024. Wellcome Open Res. 2024. PMID: 38854693 Free PMC article.
Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study.
Mbangiwa T, Sturny-Leclère A, Lechiile K, Kajanga C, Boyer-Chammard T, Hoving JC, Leeme T, Moyo M, Youssouf N, Lawrence DS, Mwandumba H, Mosepele M, Harrison TS, Jarvis JN, Lortholary O, Alanio A; AMBITION Study Group. Mbangiwa T, et al. Lancet Microbe. 2024 Mar;5(3):e261-e271. doi: 10.1016/S2666-5247(23)00362-2. Epub 2024 Feb 8. Lancet Microbe. 2024. PMID: 38342110 Free PMC article.
Cytomegalovirus viremia as a risk factor for mortality in HIV-associated cryptococcal and tuberculous meningitis.
Skipper CP, Hullsiek KH, Cresswell FV, Tadeo KK, Okirwoth M, Blackstad M, Hernandez-Alvarado N, Fernández-Alarcón C, Walukaga S, Martyn E, Ellis J, Ssebambulidde K, Tugume L, Nuwagira E, Rhein J, Meya DB, Boulware DR, Schleiss MR; ASTRO-CM and RifT Study Teams. Skipper CP, et al. Among authors: okirwoth m. Int J Infect Dis. 2022 Sep;122:785-792. doi: 10.1016/j.ijid.2022.07.035. Epub 2022 Jul 16. Int J Infect Dis. 2022. PMID: 35843498 Free PMC article.
Integrating central nervous system metagenomics and host response for diagnosis of tuberculosis meningitis and its mimics.
Ramachandran PS, Ramesh A, Creswell FV, Wapniarski A, Narendra R, Quinn CM, Tran EB, Rutakingirwa MK, Bangdiwala AS, Kagimu E, Kandole KT, Zorn KC, Tugume L, Kasibante J, Ssebambulidde K, Okirwoth M, Bahr NC, Musubire A, Skipper CP, Fouassier C, Lyden A, Serpa P, Castaneda G, Caldera S, Ahyong V, DeRisi JL, Langelier C, Crawford ED, Boulware DR, Meya DB, Wilson MR. Ramachandran PS, et al. Among authors: okirwoth m. Nat Commun. 2022 Mar 30;13(1):1675. doi: 10.1038/s41467-022-29353-x. Nat Commun. 2022. PMID: 35354815 Free PMC article.
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Singh A, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Siamisang K, Ndhlovu CE, Hlupeni A, Mutata C, van Widenfelt E, Chen T, Wang D, Hope W, Boyer-Chammard T, Loyse A, Molloy SF, Youssouf N, Lortholary O, Lalloo DG, Jaffar S, Harrison TS; Ambition Study Group. Jarvis JN, et al. N Engl J Med. 2022 Mar 24;386(12):1109-1120. doi: 10.1056/NEJMoa2111904. N Engl J Med. 2022. PMID: 35320642 Free PMC article. Clinical Trial.
Evaluation of the Diagnostic Performance of a Semiquantitative Cryptococcal Antigen Point-of-Care Assay among HIV-Infected Persons with Cryptococcal Meningitis.
Tadeo KK, Nimwesiga A, Kwizera R, Apeduno L, Martyn E, Okirwoth M, Nalintya E, Rajasingham R, Williams DA, Rhein J, Meya DB, Kafufu B, Boulware DR, Skipper CP. Tadeo KK, et al. Among authors: okirwoth m. J Clin Microbiol. 2021 Jul 19;59(8):e0086021. doi: 10.1128/JCM.00860-21. Epub 2021 Jul 19. J Clin Microbiol. 2021. PMID: 34076472 Free PMC article.
High-Dose Oral and Intravenous Rifampicin for the Treatment of Tuberculous Meningitis in Predominantly Human Immunodeficiency Virus (HIV)-Positive Ugandan Adults: A Phase II Open-Label Randomized Controlled Trial.
Cresswell FV, Meya DB, Kagimu E, Grint D, Te Brake L, Kasibante J, Martyn E, Rutakingirwa M, Quinn CM, Okirwoth M, Tugume L, Ssembambulidde K, Musubire AK, Bangdiwala AS, Buzibye A, Muzoora C, Svensson EM, Aarnoutse R, Boulware DR, Elliott AM. Cresswell FV, et al. Among authors: okirwoth m. Clin Infect Dis. 2021 Sep 7;73(5):876-884. doi: 10.1093/cid/ciab162. Clin Infect Dis. 2021. PMID: 33693537 Free PMC article. Clinical Trial.
Cerebrospinal Fluid Lactate as a Prognostic Marker of Disease Severity and Mortality in Cryptococcal Meningitis.
Abassi M, Bangdiwala AS, Nuwagira E, Kandole Tadeo K, Okirwoth M, Williams DA, Mpoza E, Tugume L, Ssebambulidde K, Huppler Hullsiek K, Musubire AK, Muzoora C, Rhein J, Meya DB, Boulware DR. Abassi M, et al. Among authors: okirwoth m. Clin Infect Dis. 2021 Nov 2;73(9):e3077-e3082. doi: 10.1093/cid/ciaa1749. Clin Infect Dis. 2021. PMID: 33249459 Free PMC article.
16 results