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Anti-SARS-CoV-2 gapmer antisense oligonucleotides targeting the main protease region of viral RNA.
Yamasaki M, Saso W, Yamamoto T, Sato M, Takagi H, Hasegawa T, Kozakura Y, Yokoi H, Ohashi H, Tsuchimoto K, Hashimoto R, Fukushi S, Uda A, Muramatsu M, Takayama K, Maeda K, Takahashi Y, Nagase T, Watashi K. Yamasaki M, et al. Among authors: takayama k. Antiviral Res. 2024 Oct;230:105992. doi: 10.1016/j.antiviral.2024.105992. Epub 2024 Aug 23. Antiviral Res. 2024. PMID: 39181215
Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells.
Hashimoto R, Sakamoto A, Deguchi S, Yi R, Sano E, Hotta A, Takahashi K, Yamanaka S, Takayama K. Hashimoto R, et al. Among authors: takayama k. Mol Ther Nucleic Acids. 2021 Dec 3;26:1107-1114. doi: 10.1016/j.omtn.2021.10.016. Epub 2021 Oct 20. Mol Ther Nucleic Acids. 2021. PMID: 34692233 Free PMC article.
Cell response analysis in SARS-CoV-2 infected bronchial organoids.
Sano E, Suzuki T, Hashimoto R, Itoh Y, Sakamoto A, Sakai Y, Saito A, Okuzaki D, Motooka D, Muramoto Y, Noda T, Takasaki T, Sakuragi JI, Minami S, Kobayashi T, Yamamoto T, Matsumura Y, Nagao M, Okamoto T, Takayama K. Sano E, et al. Among authors: takayama k. Commun Biol. 2022 May 30;5(1):516. doi: 10.1038/s42003-022-03499-2. Commun Biol. 2022. PMID: 35637255 Free PMC article.
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.
Hashimoto R, Takahashi J, Shirakura K, Funatsu R, Kosugi K, Deguchi S, Yamamoto M, Tsunoda Y, Morita M, Muraoka K, Tanaka M, Kanbara T, Tanaka S, Tamiya S, Tokunoh N, Kawai A, Ikawa M, Ono C, Tachibana K, Kondoh M, Obana M, Matsuura Y, Ohsumi A, Noda T, Yamamoto T, Yoshioka Y, Torisawa YS, Date H, Fujio Y, Nagao M, Takayama K, Okada Y. Hashimoto R, et al. Among authors: takayama k. Sci Adv. 2022 Sep 23;8(38):eabo6783. doi: 10.1126/sciadv.abo6783. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129989 Free PMC article.
2,237 results