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Transient downregulation of NR4A1 leads to impaired osteoblast differentiation through the TGF-ß pathway, and Elesclomol (STA-4783) rescues this phenotype.
Muthurangan M, Elsafadi M, Siyal A, Kaimkhani ZA, Umrani A, AlMuraikhi NA, Alfayez M, Abdelhady EE, Alqahtani H, Basavarajappa S, Aboul-Soud MAM, Mahmood A. Muthurangan M, et al. Among authors: umrani a. Cell Biochem Funct. 2023 Jul;41(5):590-598. doi: 10.1002/cbf.3814. Epub 2023 May 24. Cell Biochem Funct. 2023. PMID: 37222456