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Comparison of the metabolism of 10 chemicals in human and pig skin explants.
Géniès C, Jamin EL, Debrauwer L, Zalko D, Person EN, Eilstein J, Grégoire S, Schepky A, Lange D, Ellison C, Roe A, Salhi S, Cubberley R, Hewitt NJ, Rothe H, Klaric M, Duplan H, Jacques-Jamin C. Géniès C, et al. Among authors: hewitt nj. J Appl Toxicol. 2019 Feb;39(2):385-397. doi: 10.1002/jat.3730. Epub 2018 Oct 21. J Appl Toxicol. 2019. PMID: 30345528 Free PMC article.
Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol.
Hewitt NJ, Grégoire S, Cubberley R, Duplan H, Eilstein J, Ellison C, Lester C, Fabian E, Fernandez J, Géniès C, Jacques-Jamin C, Klaric M, Rothe H, Sorrell I, Lange D, Schepky A. Hewitt NJ, et al. J Appl Toxicol. 2020 Mar;40(3):403-415. doi: 10.1002/jat.3913. Epub 2019 Dec 22. J Appl Toxicol. 2020. PMID: 31867769 Free PMC article.
Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics-relevant chemicals.
Eilstein J, Grégoire S, Fabre A, Arbey E, Géniès C, Duplan H, Rothe H, Ellison C, Cubberley R, Schepky A, Lange D, Klaric M, Hewitt NJ, Jacques-Jamin C. Eilstein J, et al. Among authors: hewitt nj. J Appl Toxicol. 2020 Mar;40(3):416-433. doi: 10.1002/jat.3914. Epub 2020 Jan 8. J Appl Toxicol. 2020. PMID: 31912921
Suitability of different reconstructed human skin models in the skin and liver Chip2 microphysiological model to investigate the kinetics and first-pass skin metabolism of the hair dye, 4-amino-2-hydroxytoluene.
Brandmair K, Tao TP, Gerlach S, Przibilla J, Schepky A, Marx U, Hewitt NJ, Kühnl J, Maschmeyer I. Brandmair K, et al. Among authors: hewitt nj. J Appl Toxicol. 2024 Mar;44(3):333-343. doi: 10.1002/jat.4542. Epub 2023 Sep 12. J Appl Toxicol. 2024. PMID: 37699698 Free article.
88 results