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A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome.
Ahuja K, Vandenabeele M, Nami F, Lefevere E, Van Hoecke J, Bergmans S, Claes M, Vervliet T, Neyrinck K, Burg T, De Herdt D, Bhaskar P, Zhu Y, Looser ZJ, Loncke J, Gsell W, Plaas M, Agostinis P, Swinnen JV, Van Den Bosch L, Bultynck G, Saab AS, Wolfs E, Chai YC, Himmelreich U, Verfaillie C, Moons L, De Groef L. Ahuja K, et al. Among authors: van den bosch l. Acta Neuropathol Commun. 2024 Aug 28;12(1):140. doi: 10.1186/s40478-024-01851-7. Acta Neuropathol Commun. 2024. PMID: 39198924 Free PMC article.
Neuronal overexpression of IP₃ receptor 2 is detrimental in mutant SOD1 mice.
Staats KA, Bogaert E, Hersmus N, Jaspers T, Luyten T, Bultynck G, Parys JB, Hisatsune C, Mikoshiba K, Van Damme P, Robberecht W, Van Den Bosch L. Staats KA, et al. Among authors: van damme p, van den bosch l. Biochem Biophys Res Commun. 2012 Dec 14;429(3-4):210-3. doi: 10.1016/j.bbrc.2012.10.094. Epub 2012 Nov 3. Biochem Biophys Res Commun. 2012. PMID: 23131553
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.
Raitano S, Ordovàs L, De Muynck L, Guo W, Espuny-Camacho I, Geraerts M, Khurana S, Vanuytsel K, Tóth BI, Voets T, Vandenberghe R, Cathomen T, Van Den Bosch L, Vanderhaeghen P, Van Damme P, Verfaillie CM. Raitano S, et al. Among authors: van damme p, van den bosch l. Stem Cell Reports. 2015 Jan 13;4(1):16-24. doi: 10.1016/j.stemcr.2014.12.001. Epub 2014 Dec 31. Stem Cell Reports. 2015. PMID: 25556567 Free PMC article.
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.
Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM. Ordovás L, et al. Among authors: van den bosch l. Stem Cell Reports. 2015 Nov 10;5(5):918-931. doi: 10.1016/j.stemcr.2015.09.004. Epub 2015 Oct 8. Stem Cell Reports. 2015. PMID: 26455413 Free PMC article.
Inside out: the role of nucleocytoplasmic transport in ALS and FTLD.
Boeynaems S, Bogaert E, Van Damme P, Van Den Bosch L. Boeynaems S, et al. Among authors: van damme p, van den bosch l. Acta Neuropathol. 2016 Aug;132(2):159-173. doi: 10.1007/s00401-016-1586-5. Epub 2016 Jun 6. Acta Neuropathol. 2016. PMID: 27271576 Free PMC article. Review.
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, Ordovás L, Patel A, Welters M, Vanwelden T, Geens N, Tricot T, Benoy V, Steyaert J, Lefebvre-Omar C, Boesmans W, Jarpe M, Sterneckert J, Wegner F, Petri S, Bohl D, Vanden Berghe P, Robberecht W, Van Damme P, Verfaillie C, Van Den Bosch L. Guo W, et al. Among authors: van damme p, van den bosch l. Nat Commun. 2017 Oct 11;8(1):861. doi: 10.1038/s41467-017-00911-y. Nat Commun. 2017. PMID: 29021520 Free PMC article.
Energy metabolism in ALS: an underappreciated opportunity?
Vandoorne T, De Bock K, Van Den Bosch L. Vandoorne T, et al. Among authors: van den bosch l. Acta Neuropathol. 2018 Apr;135(4):489-509. doi: 10.1007/s00401-018-1835-x. Epub 2018 Mar 16. Acta Neuropathol. 2018. PMID: 29549424 Free PMC article. Review.
Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis.
Rué L, Oeckl P, Timmers M, Lenaerts A, van der Vos J, Smolders S, Poppe L, de Boer A, Van Den Bosch L, Van Damme P, Weishaupt JH, Ludolph AC, Otto M, Robberecht W, Lemmens R. Rué L, et al. Among authors: van der vos j, van damme p, van den bosch l. Acta Neuropathol Commun. 2019 Jul 12;7(1):114. doi: 10.1186/s40478-019-0759-6. Acta Neuropathol Commun. 2019. PMID: 31300041 Free PMC article.
328 results