Vandenberg JI - Search Results

1

Potassium dependent structural changes in the selectivity filter of HERG potassium channels.

Lau CHY, Flood E, Hunter MJ, Williams-Noonan BJ, Corbett KM, Ng CA, Bouwer JC, Stewart AG, Perozo E, Allen TW, Vandenberg JI. Lau CHY, et al. Among authors: vandenberg ji. Nat Commun. 2024 Aug 29;15(1):7470. doi: 10.1038/s41467-024-51208-w. Nat Commun. 2024. PMID: 39209832 Free PMC article.

2

The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics.

Vandenberg JI, Torres AM, Campbell TJ, Kuchel PW. Vandenberg JI, et al. Eur Biophys J. 2004 Apr;33(2):89-97. doi: 10.1007/s00249-003-0338-3. Epub 2003 Sep 10. Eur Biophys J. 2004. PMID: 13680209 Review.

3

Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel.

Subbiah RN, Clarke CE, Smith DJ, Zhao J, Campbell TJ, Vandenberg JI. Subbiah RN, et al. Among authors: vandenberg ji. J Physiol. 2004 Jul 15;558(Pt 2):417-31. doi: 10.1113/jphysiol.2004.062588. Epub 2004 Jun 4. J Physiol. 2004. PMID: 15181157 Free PMC article.

4

Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed.

Subbiah RN, Kondo M, Campbell TJ, Vandenberg JI. Subbiah RN, et al. Among authors: vandenberg ji. J Physiol. 2005 Dec 1;569(Pt 2):367-79. doi: 10.1113/jphysiol.2005.097386. Epub 2005 Sep 15. J Physiol. 2005. PMID: 16166152 Free PMC article.

5

Temperature dependence of human ether-a-go-go-related gene K+ currents.

Vandenberg JI, Varghese A, Lu Y, Bursill JA, Mahaut-Smith MP, Huang CL. Vandenberg JI, et al. Am J Physiol Cell Physiol. 2006 Jul;291(1):C165-75. doi: 10.1152/ajpcell.00596.2005. Epub 2006 Feb 1. Am J Physiol Cell Physiol. 2006. PMID: 16452156 Free article.

6

Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.

Clarke CE, Hill AP, Zhao J, Kondo M, Subbiah RN, Campbell TJ, Vandenberg JI. Clarke CE, et al. Among authors: vandenberg ji. J Physiol. 2006 Jun 1;573(Pt 2):291-304. doi: 10.1113/jphysiol.2006.108332. Epub 2006 Mar 23. J Physiol. 2006. PMID: 16556651 Free PMC article.

7

Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1.

Hill AP, Sunde M, Campbell TJ, Vandenberg JI. Hill AP, et al. Among authors: vandenberg ji. Biophys J. 2007 Jun 1;92(11):3915-29. doi: 10.1529/biophysj.106.101956. Epub 2007 Mar 16. Biophys J. 2007. PMID: 17369411 Free PMC article.

8

The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErg1.

Hill AP, Campbell TJ, Bansal PS, Kuchel PW, Vandenberg JI. Hill AP, et al. Among authors: vandenberg ji. Biophys J. 2007 Sep 15;93(6):L32-4. doi: 10.1529/biophysj.107.114561. Epub 2007 Jul 13. Biophys J. 2007. PMID: 17631536 Free PMC article.

9

Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels.

Perrin MJ, Kuchel PW, Campbell TJ, Vandenberg JI. Perrin MJ, et al. Among authors: vandenberg ji. Mol Pharmacol. 2008 Nov;74(5):1443-52. doi: 10.1124/mol.108.049056. Epub 2008 Aug 13. Mol Pharmacol. 2008. PMID: 18701618

10

The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel.

Ju P, Pages G, Riek RP, Chen PC, Torres AM, Bansal PS, Kuyucak S, Kuchel PW, Vandenberg JI. Ju P, et al. Among authors: vandenberg ji. J Biol Chem. 2009 Jan 9;284(2):1000-8. doi: 10.1074/jbc.M806400200. Epub 2008 Nov 7. J Biol Chem. 2009. PMID: 18996846 Free article.

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