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An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function.
Kambali M, Li Y, Unichenko P, Feria Pliego JA, Yadav R, Liu J, McGuinness P, Cobb JG, Wang M, Nagarajan R, Lyu J, Vongsouthi V, Jackson CJ, Engin E, Coyle JT, Shin J, Hodgson NW, Hensch TK, Talkowski ME, Homanics GE, Bolshakov VY, Henneberger C, Rudolph U. Kambali M, et al. Among authors: henneberger c. Mol Psychiatry. 2024 Aug 30. doi: 10.1038/s41380-024-02711-5. Online ahead of print. Mol Psychiatry. 2024. PMID: 39210012
A marker chromosome in psychosis identifies glycine decarboxylase (GLDC) as a novel regulator of neuronal and synaptic function in the hippocampus.
Kambali M, Li Y, Unichenko P, Pliego JF, Yadav R, Liu J, McGuinness P, Cobb JG, Wang M, Nagarajan R, Lyu J, Vongsouthi V, Jackson CJ, Engin E, Coyle JT, Shin J, Talkowski ME, Homanics GE, Bolshakov VY, Henneberger C, Rudolph U. Kambali M, et al. Among authors: henneberger c. bioRxiv [Preprint]. 2023 May 29:2023.05.29.542745. doi: 10.1101/2023.05.29.542745. bioRxiv. 2023. PMID: 37398055 Free PMC article. Preprint.
Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS.
Zhang WH, Herde MK, Mitchell JA, Whitfield JH, Wulff AB, Vongsouthi V, Sanchez-Romero I, Gulakova PE, Minge D, Breithausen B, Schoch S, Janovjak H, Jackson CJ, Henneberger C. Zhang WH, et al. Among authors: henneberger c. Nat Chem Biol. 2018 Sep;14(9):861-869. doi: 10.1038/s41589-018-0108-2. Epub 2018 Jul 30. Nat Chem Biol. 2018. PMID: 30061718
A Rationally and Computationally Designed Fluorescent Biosensor for d-Serine.
Vongsouthi V, Whitfield JH, Unichenko P, Mitchell JA, Breithausen B, Khersonsky O, Kremers L, Janovjak H, Monai H, Hirase H, Fleishman SJ, Henneberger C, Jackson CJ. Vongsouthi V, et al. Among authors: henneberger c. ACS Sens. 2021 Nov 26;6(11):4193-4205. doi: 10.1021/acssensors.1c01803. Epub 2021 Nov 16. ACS Sens. 2021. PMID: 34783546
Overview Article Astrocytes as Initiators of Epilepsy.
Henning L, Unichenko P, Bedner P, Steinhäuser C, Henneberger C. Henning L, et al. Among authors: henneberger c. Neurochem Res. 2023 Apr;48(4):1091-1099. doi: 10.1007/s11064-022-03773-z. Epub 2022 Oct 16. Neurochem Res. 2023. PMID: 36244037 Free PMC article. Review.
Local Efficacy of Glutamate Uptake Decreases with Synapse Size.
Herde MK, Bohmbach K, Domingos C, Vana N, Komorowska-Müller JA, Passlick S, Schwarz I, Jackson CJ, Dietrich D, Schwarz MK, Henneberger C. Herde MK, et al. Among authors: henneberger c. Cell Rep. 2020 Sep 22;32(12):108182. doi: 10.1016/j.celrep.2020.108182. Cell Rep. 2020. PMID: 32966786 Free article.
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