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The big tau splice isoform resists Alzheimer's-related pathological changes.
Chung DC, Deng X, Yalamanchili HK, Revelli JP, Han AL, Tadros B, Richman R, Dias M, Naini FA, Boeynaems S, Hyman BT, Zoghbi HY. Chung DC, et al. Among authors: boeynaems s. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605685. doi: 10.1101/2024.07.30.605685. bioRxiv. 2024. PMID: 39211086 Free PMC article. Preprint.
Arabidopsis thaliana RHAMNOSE 1 condensate formation drives UDP-rhamnose synthesis.
Field S, Dorone Y, Dwyer WP, Cox JA, Raba D, Froehlich J, Blea M, Carmo OMS, Wallace IS, Hastings R, Boeynaems S, Rhee SY. Field S, et al. Among authors: boeynaems s. bioRxiv [Preprint]. 2024 Feb 19:2024.02.15.580454. doi: 10.1101/2024.02.15.580454. bioRxiv. 2024. PMID: 38464008 Free PMC article. Preprint.
Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.
Boeynaems S, Dorone Y, Zhuang Y, Shabardina V, Huang G, Marian A, Kim G, Sanyal A, Şen NE, Griffith D, Docampo R, Lasker K, Ruiz-Trillo I, Auburger G, Holehouse AS, Kabashi E, Lin Y, Gitler AD. Boeynaems S, et al. Mol Cell. 2023 Jun 15;83(12):2020-2034.e6. doi: 10.1016/j.molcel.2023.05.025. Epub 2023 Jun 8. Mol Cell. 2023. PMID: 37295429 Free PMC article.
Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease.
Boeynaems S, Ma XR, Yeong V, Ginell GM, Chen JH, Blum JA, Nakayama L, Sanyal A, Briner A, Haver DV, Pauwels J, Ekman A, Schmidt HB, Sundararajan K, Porta L, Lasker K, Larabell C, Hayashi MAF, Kundaje A, Impens F, Obermeyer A, Holehouse AS, Gitler AD. Boeynaems S, et al. bioRxiv [Preprint]. 2023 Mar 9:2023.03.09.531820. doi: 10.1101/2023.03.09.531820. bioRxiv. 2023. PMID: 36945394 Free PMC article. Preprint.
Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Xu WQ, Cheah JS, Xu C, Messing J, Freibaum BD, Boeynaems S, Taylor JP, Udeshi ND, Carr SA, Ting AY. Xu WQ, et al. Among authors: boeynaems s. bioRxiv [Preprint]. 2023 Feb 8:2023.02.07.527548. doi: 10.1101/2023.02.07.527548. bioRxiv. 2023. Update in: Cell. 2023 Jul 20;186(15):3307-3324.e30. doi: 10.1016/j.cell.2023.05.044 PMID: 36798302 Free PMC article. Updated. Preprint.
You're in then you're out.
Onuchic P, Boeynaems S. Onuchic P, et al. Among authors: boeynaems s. Nat Chem Biol. 2023 Apr;19(4):399-400. doi: 10.1038/s41589-022-01254-6. Nat Chem Biol. 2023. PMID: 36747053 No abstract available.
Phase Separation in Biology and Disease; Current Perspectives and Open Questions.
Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, Stachowiak J, Weber SC, White M, Zhang H, Zweckstetter M, Elbaum-Garfinkle S, Kriwacki R. Boeynaems S, et al. J Mol Biol. 2023 Mar 1;435(5):167971. doi: 10.1016/j.jmb.2023.167971. Epub 2023 Jan 21. J Mol Biol. 2023. PMID: 36690068 Free PMC article.
39 results