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Amyloid age and tau PET timeline to symptomatic Alzheimer's disease in Down syndrome.
Schworer EK, Zammit MD, Wang J, Handen BL, Betthauser T, Laymon CM, Tudorascu DL, Cohen AD, Zaman SH, Ances BM, Mapstone M, Head E, Klunk WE, Christian BT, Hartley SL; Alzheimer Biomarker Consortium – Down Syndrome (ABC-DS). Schworer EK, et al. Among authors: zammit md. medRxiv [Preprint]. 2024 Aug 9:2024.08.08.24311702. doi: 10.1101/2024.08.08.24311702. medRxiv. 2024. PMID: 39211859 Free PMC article. Preprint.
Amyloid accumulation in Down syndrome measured with amyloid load.
Zammit MD, Laymon CM, Betthauser TJ, Cody KA, Tudorascu DL, Minhas DS, Sabbagh MN, Johnson SC, Zaman SH, Mathis CA, Klunk WE, Handen BL, Cohen AD, Christian BT. Zammit MD, et al. Alzheimers Dement (Amst). 2020 Apr 16;12(1):e12020. doi: 10.1002/dad2.12020. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32435686 Free PMC article.
Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline.
Tudorascu DL, Laymon CM, Zammit M, Minhas DS, Anderson SJ, Ellison PA, Zaman S, Ances BM, Sabbagh M, Johnson SC, Mathis CA, Klunk WE, Handen BL, Christian BT, Cohen AD. Tudorascu DL, et al. Alzheimers Dement (N Y). 2020 Oct 31;6(1):e12096. doi: 10.1002/trc2.12096. eCollection 2020. Alzheimers Dement (N Y). 2020. PMID: 33163613 Free PMC article.
PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome.
Zammit MD, Tudorascu DL, Laymon CM, Hartley SL, Zaman SH, Ances BM, Johnson SC, Stone CK, Mathis CA, Klunk WE, Cohen AD, Handen BL, Christian BT. Zammit MD, et al. Neuroimage. 2021 Mar;228:117728. doi: 10.1016/j.neuroimage.2021.117728. Epub 2021 Jan 7. Neuroimage. 2021. PMID: 33421595 Free PMC article.
29 results