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Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.
Wang K, Coutifaris P, Brocks D, Wang G, Azar T, Solis S, Nandi A, Anderson S, Han N, Manne S, Kiner E, Sachar C, Lucas M, George S, Yan PK, Kier MW, Laughlin AI, Kothari S, Giles J, Mathew D, Ghinnagow R, Alanio C, Flowers A, Xu W, Tenney DJ, Xu X, Amaravadi RK, Karakousis GC, Schuchter LM, Buggert M, Oldridge D, Minn AJ, Blank C, Weber JS, Mitchell TC, Farwell MD, Herati RS, Huang AC. Wang K, et al. Among authors: tenney dj. Cancer Cell. 2024 Sep 9;42(9):1582-1597.e10. doi: 10.1016/j.ccell.2024.08.007. Epub 2024 Aug 29. Cancer Cell. 2024. PMID: 39214097
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma.
Campbell KM, Amouzgar M, Pfeiffer SM, Howes TR, Medina E, Travers M, Steiner G, Weber JS, Wolchok JD, Larkin J, Hodi FS, Boffo S, Salvador L, Tenney D, Tang T, Thompson MA, Spencer CN, Wells DK, Ribas A. Campbell KM, et al. Cancer Cell. 2023 Apr 10;41(4):791-806.e4. doi: 10.1016/j.ccell.2023.03.010. Cancer Cell. 2023. PMID: 37037616 Free PMC article.
Development, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer.
Kim J, Donnelly DJ, Tran T, Pena A, Shorts AO, Petrone TV, Zhang Y, Boy KM, Scola PM, Tenney DJ, Poss MA, Soars MG, Bonacorsi SJ Jr, Cole EL, Grootendorst DJ, Chow PL, Meanwell NA, Du S. Kim J, et al. Among authors: tenney dj. Mol Imaging Biol. 2024 Apr;26(2):301-309. doi: 10.1007/s11307-023-01889-4. Epub 2023 Dec 20. Mol Imaging Biol. 2024. PMID: 38123744 Free PMC article.
Tyrosine Protein Kinase SYK-Related Gene Signature in Baseline Immune Cells Associated with Adjuvant Immunotherapy-Induced Immune-Related Adverse Events in Melanoma.
Monson KR, Ferguson R, Handzlik JE, Xiong J, Dagayev S, Morales L, Chat V, Bunis A, Sreenivasaiah C, Dolfi S, Tenney DJ, Shao Y, Osman I, Weber JS, Kirchhoff T. Monson KR, et al. Among authors: tenney dj. Clin Cancer Res. 2024 Oct 1;30(19):4412-4423. doi: 10.1158/1078-0432.CCR-24-0900. Clin Cancer Res. 2024. PMID: 39115425
Adjuvant Therapy of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Patients With Resected Stage IIIB-D or Stage IV Melanoma (CheckMate 915).
Weber JS, Schadendorf D, Del Vecchio M, Larkin J, Atkinson V, Schenker M, Pigozzo J, Gogas H, Dalle S, Meyer N, Ascierto PA, Sandhu S, Eigentler T, Gutzmer R, Hassel JC, Robert C, Carlino MS, Di Giacomo AM, Butler MO, Muñoz-Couselo E, Brown MP, Rutkowski P, Haydon A, Grob JJ, Schachter J, Queirolo P, de la Cruz-Merino L, van der Westhuizen A, Menzies AM, Re S, Bas T, de Pril V, Braverman J, Tenney DJ, Tang H, Long GV. Weber JS, et al. Among authors: tenney dj. J Clin Oncol. 2023 Jan 20;41(3):517-527. doi: 10.1200/JCO.22.00533. Epub 2022 Sep 26. J Clin Oncol. 2023. PMID: 36162037 Free PMC article. Clinical Trial.
Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection.
Balsitis S, Gali V, Mason PJ, Chaniewski S, Levine SM, Wichroski MJ, Feulner M, Song Y, Granaldi K, Loy JK, Thompson CM, Lesniak JA, Brockus C, Kishnani N, Menne S, Cockett MI, Iyer R, Mason SW, Tenney DJ. Balsitis S, et al. Among authors: tenney dj. PLoS One. 2018 Feb 14;13(2):e0190058. doi: 10.1371/journal.pone.0190058. eCollection 2018. PLoS One. 2018. PMID: 29444087 Free PMC article.
51 results