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Unveiling the novel dual specificity protein kinases in Bacillus anthracis: identification of the first prokaryotic dual specificity tyrosine phosphorylation-regulated kinase (DYRK)-like kinase.
Arora G, Sajid A, Arulanandh MD, Singhal A, Mattoo AR, Pomerantsev AP, Leppla SH, Maiti S, Singh Y. Arora G, et al. Among authors: leppla sh. J Biol Chem. 2012 Aug 3;287(32):26749-63. doi: 10.1074/jbc.M112.351304. Epub 2012 Jun 18. J Biol Chem. 2012. PMID: 22711536 Free PMC article.
A heterodimer of a VHH (variable domains of camelid heavy chain-only) antibody that inhibits anthrax toxin cell binding linked to a VHH antibody that blocks oligomer formation is highly protective in an anthrax spore challenge model.
Moayeri M, Leysath CE, Tremblay JM, Vrentas C, Crown D, Leppla SH, Shoemaker CB. Moayeri M, et al. Among authors: leppla sh. J Biol Chem. 2015 Mar 6;290(10):6584-95. doi: 10.1074/jbc.M114.627943. Epub 2015 Jan 6. J Biol Chem. 2015. PMID: 25564615 Free PMC article.
305 results