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Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
Aebi J, Atz K, Ametamey SM, Benz J, Blaising J, Butini S, Campiani G, Carreira EM, Collin L, De Lago E, Gazzi T, Gertsch J, Gobbi L, Guba W, Fernández-Ruiz J, Fingerle J, Haider A, He Y, Heitman LH, Honer M, Hunziker D, Kuhn B, Maccarrone M, Märki HP, Martin RE, Mohr P, Mu L, Nazaré M, Nippa DF, Oddi S, O'Hara F, Pacher P, Romero J, Röver S, Rufer AC, Schibli R, Schneider G, Stepan AF, Sykes DA, Ullmer C, Van der Stelt M, Veprintsev DB, Wittwer MB, Grether U. Aebi J, et al. Among authors: grether u. Chimia (Aarau). 2024 Aug 21;78(7-8):499-512. doi: 10.2533/chimia.2024.499. Chimia (Aarau). 2024. PMID: 39221845 Free article.
An oxidation-labile traceless linker for solid-phase synthesis.
Stieber F, Grether U, Waldmann H. Stieber F, et al. Among authors: grether u. Angew Chem Int Ed Engl. 1999;38(8):1073-7. doi: 10.1002/(SICI)1521-3773(19990419)38:8<1073::AID-ANIE1073>3.0.CO;2-Y. Angew Chem Int Ed Engl. 1999. PMID: 25138498
New Insights on the mechanism of PPAR-targeted drugs.
Grether U, Klaus W, Kuhn B, Maerki HP, Mohr P, Wright MB. Grether U, et al. ChemMedChem. 2010 Dec 3;5(12):1973-6. doi: 10.1002/cmdc.201000446. ChemMedChem. 2010. PMID: 21069658 No abstract available.
G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey.
Kratochwil NA, Gatti-McArthur S, Hoener MC, Lindemann L, Christ AD, Green LG, Guba W, Martin RE, Malherbe P, Porter RH, Slack JP, Winnig M, Dehmlow H, Grether U, Hertel C, Narquizian R, Panousis CG, Kolczewski S, Steward L. Kratochwil NA, et al. Among authors: grether u. Curr Top Med Chem. 2011;11(15):1902-24. doi: 10.2174/156802611796391267. Curr Top Med Chem. 2011. PMID: 21470172
72 results