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Acetyl-DL-leucine in two individuals with REM sleep behavior disorder improves symptoms, reverses loss of striatal dopamine-transporter binding and stabilizes pathological metabolic brain pattern-case reports.
Oertel WH, Janzen A, Henrich MT, Geibl FF, Sittig E, Meles SK, Carli G, Leenders K, Booij J, Surmeier DJ, Timmermann L, Strupp M. Oertel WH, et al. Among authors: surmeier dj. Nat Commun. 2024 Sep 2;15(1):7619. doi: 10.1038/s41467-024-51502-7. Nat Commun. 2024. PMID: 39223119 Free PMC article.
Determinants of seeding and spreading of α-synuclein pathology in the brain.
Henrich MT, Geibl FF, Lakshminarasimhan H, Stegmann A, Giasson BI, Mao X, Dawson VL, Dawson TM, Oertel WH, Surmeier DJ. Henrich MT, et al. Among authors: surmeier dj. Sci Adv. 2020 Nov 11;6(46):eabc2487. doi: 10.1126/sciadv.abc2487. Print 2020 Nov. Sci Adv. 2020. PMID: 33177086 Free PMC article.
281 results