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An atlas of genetic effects on cellular composition of the tumor microenvironment.
Cai Y, Lu Z, Chen C, Zhu Y, Chen Z, Wu Z, Peng J, Zhu X, Liu Z, Li B, Zhang M, Huang J, Li Y, Liu Y, Ma Q, He C, Chen S, Tian W, Fan L, Ning C, Geng H, Xu B, Li H, Zhu X, Fang J, Wang X, Zhang S, Jin M, Huang C, Yang X, Tian J, Miao X. Cai Y, et al. Among authors: geng h. Nat Immunol. 2024 Oct;25(10):1959-1975. doi: 10.1038/s41590-024-01945-3. Epub 2024 Sep 2. Nat Immunol. 2024. PMID: 39223350
HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction.
Lu Z, Fan L, Zhang F, Huang C, Cai Y, Chen C, Li G, Zhang M, Huang J, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Ye T, Liu J, Yang X, Xu B, Zhu Y, Zhong R, Li H, Tian J, Li B, Miao X. Lu Z, et al. Among authors: geng h. Arch Toxicol. 2023 Jul;97(7):2015-2028. doi: 10.1007/s00204-023-03494-4. Epub 2023 May 28. Arch Toxicol. 2023. PMID: 37245169
Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci.
Li B, Cai Y, Chen C, Li G, Zhang M, Lu Z, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Zhu Z, Xu B, Li H, Li H, Jin M, Wang X, Zhang S, Liu J, Huang C, Yang X, Wei Y, Zhu Y, Tian J, Miao X. Li B, et al. Among authors: geng h. Cancer Res. 2023 Nov 1;83(21):3650-3666. doi: 10.1158/0008-5472.CAN-23-0251. Cancer Res. 2023. PMID: 37669142
Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk.
Ying P, Chen C, Lu Z, Chen S, Zhang M, Cai Y, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Tian W, Yang Z, Liu J, Huang C, Yang X, Xu B, Li H, Zhu X, Li N, Li B, Wei Y, Zhu Y, Tian J, Miao X. Ying P, et al. Among authors: geng h. Nat Commun. 2023 Sep 25;14(1):5958. doi: 10.1038/s41467-023-41690-z. Nat Commun. 2023. PMID: 37749132 Free PMC article.
Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy.
Ning C, Fan L, Jin M, Wang W, Hu Z, Cai Y, Chen L, Lu Z, Zhang M, Chen C, Li Y, Zhang F, Wang W, Liu Y, Chen S, Jiang Y, He C, Wang Z, Chen X, Li H, Li G, Ma Q, Geng H, Tian W, Zhang H, Liu B, Xia Q, Yang X, Liu Z, Li B, Zhu Y, Li X, Zhang S, Tian J, Miao X. Ning C, et al. Among authors: geng h. Nat Commun. 2023 Nov 30;14(1):7900. doi: 10.1038/s41467-023-43771-5. Nat Commun. 2023. PMID: 38036550 Free PMC article.
Genetic architectures of the human hippocampus and those involved in neuropsychiatric traits.
Ning C, Jin M, Cai Y, Fan L, Hu K, Lu Z, Zhang M, Chen C, Li Y, Hu N, Zhang D, Liu Y, Chen S, Jiang Y, He C, Wang Z, Cao Z, Li H, Li G, Ma Q, Geng H, Tian W, Zhang H, Yang X, Huang C, Wei Y, Li B, Zhu Y, Li X, Miao X, Tian J. Ning C, et al. Among authors: geng h. BMC Med. 2024 Oct 11;22(1):456. doi: 10.1186/s12916-024-03682-8. BMC Med. 2024. PMID: 39394562 Free PMC article.
1,897 results