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Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.
Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z. Winkler J, et al. Among authors: werb z. J Clin Invest. 2024 Sep 3;134(17):e164227. doi: 10.1172/JCI164227. J Clin Invest. 2024. PMID: 39225101 Free PMC article.
Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome.
Winkler J, Liu P, Phong K, Hinrichs JH, Ataii N, Williams K, Hadler-Olsen E, Samson S, Gartner ZJ, Fisher S, Werb Z. Winkler J, et al. Among authors: werb z. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2115308119. doi: 10.1073/pnas.2115308119. Epub 2022 Mar 9. Proc Natl Acad Sci U S A. 2022. PMID: 35263230 Free PMC article.
Cellular architecture of human brain metastases.
Gonzalez H, Mei W, Robles I, Hagerling C, Allen BM, Hauge Okholm TL, Nanjaraj A, Verbeek T, Kalavacherla S, van Gogh M, Georgiou S, Daras M, Phillips JJ, Spitzer MH, Roose JP, Werb Z. Gonzalez H, et al. Among authors: werb z. Cell. 2022 Feb 17;185(4):729-745.e20. doi: 10.1016/j.cell.2021.12.043. Epub 2022 Jan 20. Cell. 2022. PMID: 35063085 Free PMC article.
Synthetic Tuning of Domain Stoichiometry in Nanobody-Enzyme Megamolecules.
Metcalf KJ, Kimmel BR, Sykora DJ, Modica JA, Parker KA, Berens E, Dai R, Dravid VP, Werb Z, Mrksich M. Metcalf KJ, et al. Among authors: werb z. Bioconjug Chem. 2021 Jan 20;32(1):143-152. doi: 10.1021/acs.bioconjchem.0c00578. Epub 2020 Dec 10. Bioconjug Chem. 2021. PMID: 33301672 Free PMC article.
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.
Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. Maller O, et al. Among authors: werb z. Nat Mater. 2021 Apr;20(4):548-559. doi: 10.1038/s41563-020-00849-5. Epub 2020 Nov 30. Nat Mater. 2021. PMID: 33257795 Free PMC article.
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing.
Davis RT, Blake K, Ma D, Gabra MBI, Hernandez GA, Phung AT, Yang Y, Maurer D, Lefebvre AEYT, Alshetaiwi H, Xiao Z, Liu J, Locasale JW, Digman MA, Mjolsness E, Kong M, Werb Z, Lawson DA. Davis RT, et al. Among authors: werb z. Nat Cell Biol. 2020 Mar;22(3):310-320. doi: 10.1038/s41556-020-0477-0. Epub 2020 Mar 6. Nat Cell Biol. 2020. PMID: 32144411
430 results