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Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases.
Saggau C, Bacher P, Esser D, Rasa M, Meise S, Mohr N, Kohlstedt N, Hutloff A, Schacht SS, Dargvainiene J, Martini GR, Stürner KH, Schröder I, Markewitz R, Hartl J, Hastermann M, Duchow A, Schindler P, Becker M, Bautista C, Gottfreund J, Walter J, Polansky JK, Yang M, Naghavian R, Wendorff M, Schuster EM, Dahl A, Petzold A, Reinhardt S, Franke A, Wieczorek M, Henschel L, Berger D, Heine G, Holtsche M, Häußler V, Peters C, Schmidt E, Fillatreau S, Busch DH, Wandinger KP, Schober K, Martin R, Paul F, Leypoldt F, Scheffold A. Saggau C, et al. Among authors: schober k. Immunity. 2024 Oct 8;57(10):2416-2432.e8. doi: 10.1016/j.immuni.2024.08.005. Epub 2024 Sep 2. Immunity. 2024. PMID: 39226901 Free article.
T cell engineering for adoptive T cell therapy: safety and receptor avidity.
D'Ippolito E, Schober K, Nauerth M, Busch DH. D'Ippolito E, et al. Among authors: schober k. Cancer Immunol Immunother. 2019 Oct;68(10):1701-1712. doi: 10.1007/s00262-019-02395-9. Epub 2019 Sep 21. Cancer Immunol Immunother. 2019. PMID: 31542797 Free PMC article. Review.
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression.
Dötsch S, Svec M, Schober K, Hammel M, Wanisch A, Gökmen F, Jarosch S, Warmuth L, Barton J, Cicin-Sain L, D'Ippolito E, Busch DH. Dötsch S, et al. Among authors: schober k. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2200626120. doi: 10.1073/pnas.2200626120. Epub 2023 Feb 28. Proc Natl Acad Sci U S A. 2023. PMID: 36853939 Free PMC article.
295 results