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Syk inhibitors reduce tau protein phosphorylation and oligomerization.
Yamaguchi T, Hamano T, Sada K, Asano R, Kanaan NM, Sasaki H, Yen SH, Kitazaki Y, Endo Y, Enomoto S, Shirafuji N, Ikawa M, Yamamura O, Fujita Y, Aoki K, Naiki H, Morishima M, Saito Y, Murayama S, Nakamoto Y. Yamaguchi T, et al. Among authors: shirafuji n. Neurobiol Dis. 2024 Oct 15;201:106656. doi: 10.1016/j.nbd.2024.106656. Epub 2024 Sep 2. Neurobiol Dis. 2024. PMID: 39233131 Free article.
Pioglitazone prevents tau oligomerization.
Hamano T, Shirafuji N, Makino C, Yen SH, Kanaan NM, Ueno A, Suzuki J, Ikawa M, Matsunaga A, Yamamura O, Kuriyama M, Nakamoto Y. Hamano T, et al. Among authors: shirafuji n. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1035-42. doi: 10.1016/j.bbrc.2016.08.016. Epub 2016 Aug 16. Biochem Biophys Res Commun. 2016. PMID: 27543203
Rho-kinase ROCK inhibitors reduce oligomeric tau protein.
Hamano T, Shirafuji N, Yen SH, Yoshida H, Kanaan NM, Hayashi K, Ikawa M, Yamamura O, Fujita Y, Kuriyama M, Nakamoto Y. Hamano T, et al. Among authors: shirafuji n. Neurobiol Aging. 2020 May;89:41-54. doi: 10.1016/j.neurobiolaging.2019.12.009. Epub 2019 Dec 16. Neurobiol Aging. 2020. PMID: 31982202 Free PMC article.
Autophagy and Tau Protein.
Hamano T, Enomoto S, Shirafuji N, Ikawa M, Yamamura O, Yen SH, Nakamoto Y. Hamano T, et al. Among authors: shirafuji n. Int J Mol Sci. 2021 Jul 12;22(14):7475. doi: 10.3390/ijms22147475. Int J Mol Sci. 2021. PMID: 34299093 Free PMC article. Review.
Clioquinol Decreases Levels of Phosphorylated, Truncated, and Oligomerized Tau Protein.
Lin G, Zhu F, Kanaan NM, Asano R, Shirafuji N, Sasaki H, Yamaguchi T, Enomoto S, Endo Y, Ueno A, Ikawa M, Hayashi K, Yamamura O, Yen SH, Nakamoto Y, Hamano T. Lin G, et al. Among authors: shirafuji n. Int J Mol Sci. 2021 Nov 8;22(21):12063. doi: 10.3390/ijms222112063. Int J Mol Sci. 2021. PMID: 34769495 Free PMC article.
The Implications of Autophagy in Alzheimer's Disease.
Hamano T, Hayashi K, Shirafuji N, Nakamoto Y. Hamano T, et al. Among authors: shirafuji n. Curr Alzheimer Res. 2018;15(14):1283-1296. doi: 10.2174/1567205015666181004143432. Curr Alzheimer Res. 2018. PMID: 30289076 Review.
91 results