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Page 1
Pseudouridine guides germline small RNA transport and epigenetic inheritance.
Herridge RP, Dolata J, Migliori V, de Santis Alves C, Borges F, Schorn AJ, van Ex F, Lin A, Bajczyk M, Parent JS, Leonardi T, Hendrick A, Kouzarides T, Martienssen RA. Herridge RP, et al. Among authors: kouzarides t. Nat Struct Mol Biol. 2024 Sep 6. doi: 10.1038/s41594-024-01392-6. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39242979
Pseudouridine guides germline small RNA transport and epigenetic inheritance.
Herridge RP, Dolata J, Migliori V, de Santis Alves C, Borges F, Schorn AJ, Van Ex F, Parent JS, Lin A, Bajczyk M, Leonardi T, Hendrick A, Kouzarides T, Martienssen RA. Herridge RP, et al. Among authors: kouzarides t. bioRxiv [Preprint]. 2023 Nov 3:2023.05.27.542553. doi: 10.1101/2023.05.27.542553. bioRxiv. 2023. Update in: Nat Struct Mol Biol. 2024 Sep 6. doi: 10.1038/s41594-024-01392-6 PMID: 37398006 Free PMC article. Updated. Preprint.
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control.
Barbieri I, Tzelepis K, Pandolfini L, Shi J, Millán-Zambrano G, Robson SC, Aspris D, Migliori V, Bannister AJ, Han N, De Braekeleer E, Ponstingl H, Hendrick A, Vakoc CR, Vassiliou GS, Kouzarides T. Barbieri I, et al. Among authors: kouzarides t. Nature. 2017 Dec 7;552(7683):126-131. doi: 10.1038/nature24678. Epub 2017 Nov 27. Nature. 2017. PMID: 29186125 Free PMC article.
RNA modifications detection by comparative Nanopore direct RNA sequencing.
Leger A, Amaral PP, Pandolfini L, Capitanchik C, Capraro F, Miano V, Migliori V, Toolan-Kerr P, Sideri T, Enright AJ, Tzelepis K, van Werven FJ, Luscombe NM, Barbieri I, Ule J, Fitzgerald T, Birney E, Leonardi T, Kouzarides T. Leger A, et al. Among authors: kouzarides t. Nat Commun. 2021 Dec 10;12(1):7198. doi: 10.1038/s41467-021-27393-3. Nat Commun. 2021. PMID: 34893601 Free PMC article.
METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation.
Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. Pandolfini L, et al. Among authors: kouzarides t. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25. Mol Cell. 2019. PMID: 31031083 Free PMC article.
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Yankova E, Blackaby W, Albertella M, Rak J, De Braekeleer E, Tsagkogeorga G, Pilka ES, Aspris D, Leggate D, Hendrick AG, Webster NA, Andrews B, Fosbeary R, Guest P, Irigoyen N, Eleftheriou M, Gozdecka M, Dias JML, Bannister AJ, Vick B, Jeremias I, Vassiliou GS, Rausch O, Tzelepis K, Kouzarides T. Yankova E, et al. Among authors: kouzarides t. Nature. 2021 May;593(7860):597-601. doi: 10.1038/s41586-021-03536-w. Epub 2021 Apr 26. Nature. 2021. PMID: 33902106 Free PMC article.
Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication.
Santos-Rosa H, Millán-Zambrano G, Han N, Leonardi T, Klimontova M, Nasiscionyte S, Pandolfini L, Tzelepis K, Bartke T, Kouzarides T. Santos-Rosa H, et al. Among authors: kouzarides t. Mol Cell. 2021 Jul 1;81(13):2793-2807.e8. doi: 10.1016/j.molcel.2021.04.021. Epub 2021 May 11. Mol Cell. 2021. PMID: 33979575 Free PMC article.
RNA-modifying enzymes and their function in a chromatin context.
Tzelepis K, Rausch O, Kouzarides T. Tzelepis K, et al. Among authors: kouzarides t. Nat Struct Mol Biol. 2019 Oct;26(10):858-862. doi: 10.1038/s41594-019-0312-0. Epub 2019 Oct 3. Nat Struct Mol Biol. 2019. PMID: 31582848 Free PMC article. Review.
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci.
Amaral PP, Leonardi T, Han N, Viré E, Gascoigne DK, Arias-Carrasco R, Büscher M, Pandolfini L, Zhang A, Pluchino S, Maracaja-Coutinho V, Nakaya HI, Hemberg M, Shiekhattar R, Enright AJ, Kouzarides T. Amaral PP, et al. Among authors: kouzarides t. Genome Biol. 2018 Mar 15;19(1):32. doi: 10.1186/s13059-018-1405-5. Genome Biol. 2018. PMID: 29540241 Free PMC article.
Targeting the m6A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication.
Burgess HM, Depledge DP, Thompson L, Srinivas KP, Grande RC, Vink EI, Abebe JS, Blackaby WP, Hendrick A, Albertella MR, Kouzarides T, Stapleford KA, Wilson AC, Mohr I. Burgess HM, et al. Among authors: kouzarides t. Genes Dev. 2021 Jul 1;35(13-14):1005-1019. doi: 10.1101/gad.348320.121. Epub 2021 Jun 24. Genes Dev. 2021. PMID: 34168039 Free PMC article.
203 results