Lorenzo S - Search Results

1

Dose Justification for Asciminib in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia with and Without the T315I Mutation.

Combes FP, Sy SKB, Li YF, Lorenzo S, Dasgupta K, Kapoor S, Hoch M, Ho YY. Combes FP, et al. Among authors: lorenzo s. Clin Pharmacokinet. 2024 Sep;63(9):1301-1312. doi: 10.1007/s40262-024-01411-1. Epub 2024 Sep 7. Clin Pharmacokinet. 2024. PMID: 39243304 Free PMC article. Clinical Trial.

2

Population Pharmacokinetics of Asciminib in Tyrosine Kinase Inhibitor-Treated Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic and Acute Phases.

Li YF, Combes FP, Hoch M, Lorenzo S, Sy SKB, Ho YY. Li YF, et al. Among authors: lorenzo s. Clin Pharmacokinet. 2022 Oct;61(10):1393-1403. doi: 10.1007/s40262-022-01148-9. Epub 2022 Jun 28. Clin Pharmacokinet. 2022. PMID: 35764773 Clinical Trial.

3

Exposure-Efficacy Analysis of Asciminib in Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase.

Combes FP, Li YF, Hoch M, Lorenzo S, Ho YY, Sy SKB. Combes FP, et al. Among authors: lorenzo s. Clin Pharmacol Ther. 2022 Nov;112(5):1040-1050. doi: 10.1002/cpt.2699. Epub 2022 Jul 31. Clin Pharmacol Ther. 2022. PMID: 35776072 Clinical Trial.

4

Correction to: Population Pharmacokinetics of Asciminib in Tyrosine Kinase Inhibitor-Treated Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic and Acute Phases.

Li YF, Combes FP, Hoch M, Lorenzo S, Sy SKB, Ho YY. Li YF, et al. Among authors: lorenzo s. Clin Pharmacokinet. 2022 Oct;61(10):1475-1476. doi: 10.1007/s40262-022-01166-7. Clin Pharmacokinet. 2022. PMID: 35976571 No abstract available.

5

Pharmacokinetics and Safety of Multiple-Dose Alpelisib in Participants with Moderate or Severe Hepatic Impairment: A Phase 1, Open-Label, Parallel Group Study.

Marbury T, El-Hashimy M, Blumenstein L, Letellier F, Sengupta T, Lorenzo S, Preston RA. Marbury T, et al. Among authors: lorenzo s. J Cancer. 2023 May 21;14(9):1571-1578. doi: 10.7150/jca.82736. eCollection 2023. J Cancer. 2023. PMID: 37325049 Free PMC article.

6

A phase-1, open-label, single-dose study of the pharmacokinetics of buparlisib in subjects with mild to severe hepatic impairment.

Csonka D, Hazell K, Waldron E, Lorenzo S, Duval V, Trandafir L, Kobalava ZD. Csonka D, et al. Among authors: lorenzo s. J Clin Pharmacol. 2016 Mar;56(3):316-23. doi: 10.1002/jcph.590. Epub 2015 Sep 14. J Clin Pharmacol. 2016. PMID: 26183800 Free PMC article. Clinical Trial.

7

Midostaurin does not prolong cardiac repolarization defined in a thorough electrocardiogram trial in healthy volunteers.

del Corral A, Dutreix C, Huntsman-Labed A, Lorenzo S, Morganroth J, Harrell R, Wang Y. del Corral A, et al. Among authors: lorenzo s. Cancer Chemother Pharmacol. 2012 May;69(5):1255-63. doi: 10.1007/s00280-012-1825-y. Cancer Chemother Pharmacol. 2012. PMID: 22294470 Free PMC article. Clinical Trial.

8

Comparison of two endogenous biomarkers of CYP3A4 activity in a drug-drug interaction study between midostaurin and rifampicin.

Dutreix C, Lorenzo S, Wang Y. Dutreix C, et al. Among authors: lorenzo s. Eur J Clin Pharmacol. 2014 Aug;70(8):915-20. doi: 10.1007/s00228-014-1675-0. Epub 2014 May 21. Eur J Clin Pharmacol. 2014. PMID: 24839948 Free PMC article. Clinical Trial.

9

Investigation into CYP3A4-mediated drug-drug interactions on midostaurin in healthy volunteers.

Dutreix C, Munarini F, Lorenzo S, Roesel J, Wang Y. Dutreix C, et al. Among authors: lorenzo s. Cancer Chemother Pharmacol. 2013 Dec;72(6):1223-34. doi: 10.1007/s00280-013-2287-6. Epub 2013 Oct 2. Cancer Chemother Pharmacol. 2013. PMID: 24085261 Free PMC article. Clinical Trial.

10

Physiologically Based Pharmacokinetic Modeling of Oral Absorption, pH, and Food Effect in Healthy Volunteers to Drive Alpelisib Formulation Selection.

Gajewska M, Blumenstein L, Kourentas A, Mueller-Zsigmondy M, Lorenzo S, Sinn A, Velinova M, Heimbach T. Gajewska M, et al. Among authors: lorenzo s. AAPS J. 2020 Oct 18;22(6):134. doi: 10.1208/s12248-020-00511-7. AAPS J. 2020. PMID: 33070288 Clinical Trial.

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